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Biomedical subjects

H N Jacklin

Publications and source records attributed to H N Jacklin.

15 recordsLinked to original sources

Falciform fold, retinal detachment, and Norrie's disease.

A patient with X-chromosome-linked recessive Norrie's disease, characterized by retinal falciform fold, retinal detachment, repeated vitreous hemorrhage, and retrolental membrane formation, was observed from age 6 weeks. The patient showed the clinical progression from these early retinal and vitreous changes to the more typical retrolental vascularized detached retina. Pathologic examination showed normal retinal tissue. Two other male relatives showed the end stages of Norrie's disease with bilateral congenital blindness, with and without mental retardation and deafness. Vitreoretinal surgery prevented phthisis bulbi from occurring the operated eye but was unsuccessful in reattaching the contracted retina.

Adolescent↗

Acute posterior multifocal placoid pigment epitheliopathy and thyroiditis.

A young woman developed the characteristic clinical and fluorescein angiographic findings of acute posterior multifocal placoid retinal pigment epitheliopathy while being treated for acute thyroiditis. Widespread involvement of the cornea, uveal tract, as well as the optic nerve and retina indicate a generalized ocular inflammation in the clinical course of this patient. The relationship between the subacute thyroiditis and acute posterior multifocal placoid retinal pigment epitheliopathy may indicate an underlying viral cause of both disorders.

Acute Disease↗

Lens surgery with the vitreous infusion suction cutter.

The vitreous infusion suction cutter was used in the removal of congenital and adult cataracts or lens remnants. The instrument may be used through a standard corneoscleral incision or through the pars plana. When a hard nucleus cannot be dispersed, ultrasonic phacofragmentation may be of help. Several brief case illustrations demonstrate the effectiveness of this instrument in lens surgery.

Adolescent↗

Cryotreatment of toxoplasmosis retinochoroiditis.

Cryotherapy was utilized in 5 eyes of 4 patients with recurrent toxoplasmosis retinochoroiditis. Each patient showed slow gradual improvement in vision over several months following cryotreatment where previous medical management had failed. No recurrences have been noted during the follow-up period of 3 months to 3 years.

Adult↗