An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde".
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Biomedical subjects
Publications and source records attributed to H N Schnitzlein.
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Correlation of findings on neurological examination of the cranial nerves with gross anatomy, neuroanatomy, and neuropathology provides the optimal diagnostic use of magnetic resonance imaging (MRI). Illustrations of the anatomy of each of the cranial nerves, with concise labeling of relevant anatomical relationships, are compared with brief neurological summaries and MRIs of patients.
Dissections of cadaver heads and studies of specimens sectioned in horizontal (axial), coronal, or sagittal planes at low (5 X) magnification revealed a frequent venous sinus within the bone of the dorsum sellae in addition to the true dural sinuses. This sinus interconnected the cavernous sinuses on either side of the sella turcica and was continuous with the superior and inferior petrosal sinuses and the basilar plexus. The sinus was quite evident on venograms of five patients. In sagittal sections of 37 adult cadaver heads, the sinus was identified in 28 (76%) and was absent in nine (24%) in which there was pneumatization of the dorsum sellae by the sphenoid sinus. The intracranial sinus of the dorsum sellae is not a true dural sinus but is comparable to the basivertebral veins of the spine.
A comparative neuroanatomical investigation of the telencephala of Division I of teleost fishes (Greenwood, Rosen, Weitzman, and Myers, 1966) has demonstrated that homologies with other vertebrates can be made on the basis of the relationships of commonly recognized fiber bundles such as the olfactory tracts, forebrain bundles and commissures as well as those of cell types in the nuclear regions. A description and illustrations of the telecephalon of a typical representative brain (American eel, Anguilla rostrata) of Division I are presented with comparisons with the other elopomorphs and with the clupeomorphs. Although the brains may differ in gross appearance, all have certain unique microscopic configurations. They lack lateral ventricles and have a dorsal membrane as do all actinopterygeans. The brains of these fishes characteristically have (1) apposed sessile (or attenuated penduncluar) olfactory bulbs (2) which lack the typical vertebrate laminar pattern, (3) the preoptic region is unusually large although (4) the recess may not extend rostral to the anterior commissure, (5) the striatal and amygdalar areas are large and especially well differentiated, and (6) a nucleus glomerulosus is lacking. Other fishes differ from those in Division I in one or more of these anatomical features. These criteria may be used to differentiate teleosts of Division I from those of other Divisions.
The spinal cord of goldfish (Carassius auratus) was examined in normal and experimental animals by light and electron microscopy. Comparisons of Golgi material and electron micrographs have shown the large ventral horn motoneurons to have dendrites with few spines. The axon may arise from a ventral dendrite. Synapses on the motoneuron may be chemical or combined electrotinic and chemical or electrotonic between dendrites. Transection of the cord produced degeneration of small boutons, but large boutons remained intact. Small boutons were found on dorsal root axons and large boutons on interneurons in Golgi preparations. Boutons en passant may arise from myelinated fibers.
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