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Biomedical subjects

H Neering

Publications and source records attributed to H Neering.

At least 37 records · Page 2Linked to original sources

Juvenile plantar dermatosis.

Juvenile plantar dermatosis seems to be a new skin disease found mainly in children between 3 and 14 years old. The main symptoms are: redness, shiny hyperkeratosis, lamellar scaling and painful fissure formation in weight-bearing parts of the soles and toes. Sometimes the hands also seem to be affected. External factors, occlusive socks and footwear, possibly together with an atopic constitution, are believed to be the cause of the disease, which is very difficult to treat. The findings in 157 published and 23 own cases are discussed.

Adolescent↗

Atypical fibroxanthoma of the skin. Presentation of 5 cases and a review of the literature.

A typical fibroxanthoma is a solitary tumour of the skin, which occurs mostly on sun-exposed areas in elderly people. The diagnosis can only be made with certainty on the typical histological findings, which suggest a bizarre malignant tumour. Although metastasizing tumours are reported in the literature, the authors believe that the true atypical fibroxanthoma is benign. Correct diagnosis obviates the need for unnecessary radical surgery. The possibility of atypical fibroxanthoma should always be considered when a histologically bizarre tumour is found on sun-damaged or irradiation-damaged skin in elderly patients or on previously traumatized sites. In this paper five cases are added to the 346 cases culled from the literature. Electron microscopic investigations in one case demonstrated cells with delicate cytoplasmic fibrils in small bundles. This does not necessarily suggest filaments of myofibroblasts, as has been previously reported.

Aged↗

Treatment of melasma (chloasma) by local application of a steroid cream.

15 patients with melasma were treated with betamethasone 17-valerate in a cream base containing DMSO. One patient with secondary pigmentation was also entered in the trial. In nine patients results were favourable and in three results were moderate. This effect could be ascribed to the steroid.

Administration, Topical↗

Allergens in sesame oil contact dermatitis.

In 13 patients with contact allergy to sesame oil, studies were undertaken to elucidate the nature of the allergens. Sesamol, sesamin and sesamolin were identified in crude and purified (pharmaceutical) sesame oil. Patch tests showed 8 of the 13 patients to be positive to sesamol and 12 to sesamolin and sesamin. Patch tests with the pure substances on thin-layer sheets were inconclusive as to any difference between these substances. Group allergy to several substances related to sesamol could not be clearly demonstrated.

Allergens↗