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Biomedical subjects

H Oxhøj

Publications and source records attributed to H Oxhøj.

At least 19 recordsLinked to original sources

[Measurement of intestinal blood supply in patients with suspected intestinal ischemia].

The object of the investigation was to illustrate the diagnostic yields of measurement of the intestinal blood supply before and after a test meal and of abdominal angiography recorded in patients in whom chronic intestinal ischaemia is suspected. A retrospective review including 18 patients (age range 36-79 years) was undertaken. The diagnosis of chronic intestinal ischaemia was established in four patients on the basis of measurement of the blood supply to the intestine and abdominal angiography and vascular reconstructive interventions could be performed. These interventions were technically successful in three cases. Control flow measurement was only performed in one patient after the operation. This showed normalized postprandial blood flow. By large, measurements of the blood supply to the intestine were free from complications. In cases of suspected chronic intestinal ischaemia, the combination of abdominal angiography and measurement of the blood supply to the intestine appear to supply the necessary information for selection of patients for vascular surgical interventions.

Abdominal Pain

Reference values for bicycle exercise tests in patients with various degrees of ischaemic heart disease.

This investigation was carried out in an effort to analyze the influence of various degrees of ischaemic heart disease (IHD) on cardiovascular and physical performance. Assessment of the severity of IHD was based on observations obtained routinely during exercise tests (ST segment response and systolic blood pressure response). The study group included 926 subjects with known or suspected IHD, who were referred for an exercise testing; 268 females, mean age 54 years (range 19-89 years), and 658 males, mean age 52 years (range 16-88 years). We found that increasing IHD severity was associated with significant reductions of cardiovascular performance. The mean maximum work-load (MWL) was lower in females than in males, and MWL as well as mean maximum heart rate (MHR) and mean maximum change in systolic blood pressure (M delta SBP) decreased with increasing IHD and age. The present results may be used to assess the cardiovascular response to exercise in patients with IHD so that altered responses due to causes other than IHD may be identified. Furthermore the result may prove useful in the adjustment of rate responsive pacemakers (RRP) in patients with IHD.

Adolescent

[Transesophageal echocardiography. Practical experiences and diagnostic results].

Practical experience from and diagnostic yield of 65 transesophageal echocardiographies (TEE) performed routinely in 63 patients aged 10-84 are presented. TEE is performed after few preparations and with limited discomfort to the patient. Complications are rare. The results of TEE were compared with the results of conventional transthoracic echocardiography (TTE). Fifty per cent of the TEEs resulted in therapeutically relevant new information, and 25 per cent excluded suspected pathological states. The remaining 25 per cent gave more detailed information without immediate therapeutic consequences.

Adolescent

Peak flow nasal patency indices in patients operated for nasal obstruction.

In 26 patients undergoing operation for nasal obstruction, nasal and oral peak expiratory and inspiratory flow rates were measured preoperatively and 1 month postoperatively. Peak expiratory and inspiratory flow nasal patency indices were calculated from the ratio between the nasal and oral peak flow rates. Postoperatively, these indices were significantly increased for the total nose and for the preoperatively worse nasal cavity. No significant change was observed for the oral peak flow rates. A significant preoperative difference in nasal patency between the two nasal cavities was eliminated by surgery, as the postoperative peak flow of each nasal cavity reached 80% of the peak flow of the total nose on expiration and close to 50% on inspiration. A good correspondence between the subjective improvement of nasal patency and the increase in peak expiratory and inspiratory flow nasal patency indices was observed for the total nose. These findings show that peak flow nasal patency indices give valuable information pre- and post-operatively in patients undergoing nasal surgery and that the method is simple and easy to perform.

Adolescent

Entrapment of a tined pacemaker electrode in the tricuspid valve. A case report.

A tined pacemaker electrode was entrapped in the tricuspid valve apparatus. Nonresponding, sustained ventricular tachycardia, and cardiac arrest necessitated forcible removal of the electrode causing partial avulsion of the tricuspid valve. Hemodynamically insignificant tricuspid regurgitation developed subsequently.

Electrodes, Implanted

Selection of amputation level in ischemia. Skin blood flow and perfusion pressure equally predictive.

In 33 patients who had major amputation for ischemia of the lower extremity, skin blood flow and perfusion pressure were compared in terms of prediction of amputation level. Skin blood pressure was measured photoelectrically. Only the blood flow was known to the surgeon. The primary amputation was performed below the level of the knee in 15 patients, through-knee in 14, and above the knee in only 4 patients. Primary healing was achieved in 27 patients, 5 patients had delayed healing at the same level, and 1 patient was reamputated. The same amputation level was predicted in 24 patients (primary healing/secondary healing/failure = 20/3/1) and a different one in 9 patients. In 4 patients the perfusion pressure suggested a more proximal amputation (2/2/0) and in 5 patients a more distal amputation (all primary healing). There was no difference between the two methods in predicting wound healing.

Adult

[Percutaneous pulmonary balloon valvuloplasty in Denmark].

Percutaneous balloon valvuloplasty of valvular pulmonary stenosis (PPB) was carried out for the first time in 1982 and is now regarded as the primary method of treatment of this condition. The results of the first PPB treatments in Denmark are presented here. PPB was planned in 28 patients and was carried out in 25 (22 children and 3 adults). PPB was carried out on two occasions in one patient. Twenty-three patients had isolated valvular pulmonary stenosis and two patients had Fallot's anomaly. No complications of significance occurred after the treatments. The average gradient for all dilatations was 77 +/- 24 mm Hg prior to and 36 +/- 23 (p less than 0.0001) immediately after PPB. The gradient was reduced by more than 50% in 68% of the patients. In 14 patients, the gradients over the pulmonary valve was measured by Doppler technique or by cardiac catheterization greater than 6 months after PPB. In these patients, the average gradient was 69 +/- 21 mm Hg prior to PPB, 29 +/- 12 mm Hg (p less than 0.0001) immediately after PPB and 27 +/- 9 mm Hg (p less than 0.0001) at the most recent control examination, on an average 12 months (range 6-24 months) after PPB. In the same patient group, significant reduction of the electrocardiographic right-sided hypertrophy was found at the most recent control examination. It is concluded that PPB is an effective and safe treatment of valvular pulmonary stenosis.

Adolescent

Left ventricular structural changes in young men at increased risk of developing essential hypertension. Assessment by echocardiography.

Left ventricular structural changes were assessed by echocardiography in young men at increased risk of developing essential hypertension. Four groups were investigated: 28 normotensive offspring of hypertensives (NTO), 20 borderline hypertensive offspring of hypertensives (BHO), 12 borderline hypertensives with normotensive parents (BH) and 28 normotensive subjects with normotensive parents (NT). The septum-posterior wall ratio was increased in the risk groups (NT, BHO, BH). The increased ratio could be explained by both heredity and elevated blood pressure. Left ventricular mass index (LVMI) correlated strongly with physical activity in the NT group, so LVMI was adjusted accordingly. The adjusted LVMI was significantly increased in the risk groups. The increase in the adjusted LVMI could best be explained by the elevated blood pressure and not by heredity. Multivariate analysis of variance showed that physical activity is an independent predictor of LVMI only in the NT group and that systolic blood pressure is an independent predictor of LVMI only in the risk groups.

Adolescent

The effect of carotid sinus massage is independent of posture in patients with heart disease.

The influence of posture on the effect of carotid sinus massage (CSM) in patients with heart disease has not been systematically evaluated. In the present study CSM was performed in 80 patients (mean age 55 +/- 10 (SD) years) suffering from various cardiovascular diseases. Each subject had unilateral right- and left-sided CSM performed in the supine and in the sitting position, while heart rate and systolic blood pressure were monitored. No statistically significant differences in the CSM-induced response in systolic blood pressure or heart rate were found between the two postures. In the supine position the drop in heart rate was significantly greater after right-sided than after left-sided CSM (P less than 0.05). In only one patient (1%) was a significant carotid sinus reflex evoked. The response was cardioinhibitory with asystole for 3700 ms during right-sided, supine CSM. These results imply that posture does not influence the effect of CSM in patients suffering from heart disease.

Aged

Pacing in a patient with Ebstein's anomaly.

We report a case of Ebstein's anomaly in which ventricular pacing was achieved by positioning a pacing lead in the enlarged right atrium. By placing the electrode in the atrialization of the right ventricle, an aggravation of tricuspid regurgitation that may result from catheter displacement of the valve leaflets is avoided.

Adult

Pregnancy and cesarean section in a patient with a rate-responsive pacemaker.

The function of a rate-responsive pacemaker was monitored during pregnancy and cesarean section in a woman with complete atrioventricular block. The observations during pregnancy were compared to similar observations obtained in a pregnant normal woman of comparable age, height and weight, and in 12 normal women during elective cesarean section. During pregnancy, the heart rate increased in the normal woman, whereas the pacing rate in the woman with the implanted pacemaker was unchanged. Fetal movement caused an increase in pacing rate in the 37th week of gestation, whereas the heart rate in the normal woman did not respond. During cesarean section the pacing rate was generally within the mean +/- 1 SD for normal women.

Adult

Outbreak of infection with Achromobacter xylosoxidans from contaminated intravascular pressure transducers.

Achromobacter xylosoxidans contaminating transducers caused 15 cases of hospital infection. In the eight patients with bacteraemia the interval from inoculation to fever was an average of 6.6 days. All the infected patients recovered. Computerization of laboratory records allowed retrieval of previous isolates, and review of clinical records focused the problem on patients with cardiac and aortic diseases. The problem arose from the re-use of disposable equipment after disinfection with a benzalcone.

Aged