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Biomedical subjects

H P Krayenbüch

Publications and source records attributed to H P Krayenbüch.

2 recordsLinked to original sources

[2 years of clinical experiences with lithium pacemakers].

Between January 1974 and December 1976, 470 mercury-cell pacemakers and 353 lithium-cell pacemakers were implanted at Surgical Clinic A of the University Hospital of Zurich. Within the first 24 months 15.5% of the mercury-cell pacemakers had to be exchanged because of premature battery depletion and 1.3% due to dysfunction of electronic components. None of the lithium-cell pacemakers had to be removed for these reasons. In 6 lithium-cell pacemakers, however, overhaul was necessary because of sensing failure. One unit had to be removed after one year for local decubitus. In two cases, repositioning of the batteries was necessary because of local muscle stimulation.

Humans↗

[Left ventricular function in chronic pulmonary hypertension].

10 patients with chronic pulmonary hypertension (PH) consequent to primary or secondary pulmonary vascular disease and 12 control subjects were studied by left ventricular (LV) micromanometry and cineangiography. At rest, LV "total pressure" Vmax and volumetric parameters (RAO position) of the patients with PH were within normal limits. LV end-diastolic pressure, was, however, significantly increased. Biplane cineangiographic evaluation in 6 patients with PH revealed a significantly reduced LV transverse diameter in the LAO as compared to the RAO position. This finding was confirmed by echocardiography. The thickness of the LV lateral and posterior wall was normal, whereas septal thickness was significantly increased in the patients with PH. During isometric exercise Vmax increased significantly in PH but not in the controls. It is concluded that (1) in chronic PH LV function is normal at rest, (2) LV contractile reserve is inpaired and (3) apparent LV compliance is reduced due to both septal hypertrophy and abnormal LV geometry.

Cardiac Volume↗