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Biomedical subjects

H P Skejø

Publications and source records attributed to H P Skejø.

4 recordsLinked to original sources

[Atraumatic avascular necrosis of the femoral head in adults. Diagnosis and treatment].

Atraumatic avascular necrosis of the femoral head is a well-known disease which in the majority of cases is associated with conditions like alcohol abuse or steroid therapy. Early diagnosis is important, in particular in younger patients, in order to preserve the femoral head. Plain radiography, computed tomography, scintigraphy, and magnetic resonance imaging are the radiological methods used for detection of avascular necrosis, and especially magnetic resonance imaging has like scintigraphy been found to be well suited for diagnosis in early stages. Characteristic magnetic resonance scan patterns are described. Surgical treatment is necessary in most cases. Various methods are used, according to the stage of the disease.

Adult↗

[Primary cerebral non-Hodgkin's lymphoma. Intensive chemotherapy supported by crania radiotherapy].

Four cases of primary central nervous system lymphomas treated with high dose cytosine arabinoside and high dose methotrexate prior to cranial irradiation are described. All patients achieved a complete clinical and radiological remission following treatment with chemotherapy alone. Three patients are alive with a follow-up period of 60, 45 og 24 months, respectively. One patient died 12 months after diagnosis at another hospital. Autopsy was not performed.

Adult↗

[Caroli's disease].

Caroli's disease (CS) is a rare malformation of the bile duct with multiple segmental communicating dilatations of intrahepatic bile ducts affecting the whole of or parts of the liver. The disease is presumably of autosomal recessive hereditary character. Caroli described two types: the rare isolated variety (type 1), is characterized by recurring episodes of cholangitis. The more frequently occurring type 2 is associated with congenital hepatic fibrosis, and consequently there are also symptoms of portal hypertension. Both types may make their first appearance at a very early age. A case story is presented. In the light of the development of carcinoma in 7% of the patients, the authors recommend that patients who cannot be operated radically should have regular, clinical follow-ups including ultrasonography and biopsies if necessary.

Adult↗