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Biomedical subjects

H Padma-Nathan

Publications and source records attributed to H Padma-Nathan.

9 recordsLinked to original sources
PubMed1990

The microarchitecture of the intracavernosal smooth muscle and the cavernosal fibrous skeleton.

The bulk of the parenchyma of the corpora cavernosa consists of bundles of smooth muscle fibers. These bundles are oriented in all directions and establish at least 2 insertions upon elements of the fibrous skeleton of the corpora. The fibrous skeleton includes the tunica albuginea and its fibrous columns, the intracavernous fibrous framework, and the periarterial and perineural fibrous sheaths. The cavernous vascular spaces (sinusoids) form an intercommunicating network embedded within the mass of smooth muscle. Thus, the smooth muscle does not form a muscular wall proper for each sinusoid.

Collagen↗
PubMed1988

Therapeutic roles of intracavernosal papaverine.

Intracavernosal self-injection of smooth muscle relaxants, primarily papaverine admixed with phentolamine, have been used to treat impotence in over 300 patients. The program is effective in a large fraction of this group. Selection of patients, adjustment of dose, methods for monitoring, clinical efficacy, and complications are discussed.

Erectile Dysfunction↗
PubMed1988

Neurologic evaluation of erectile dysfunction.

Most patients with neurogenic impotence present with a pre-existing neurologic disease. The neurologic assessment in these patients is generally performed to confirm that the underlying neuropathology plays a role in the erectile dysfunction. There are patients, however, with no obvious pre-existing neuropathology who are identified as having a vibratory impairment of the dorsal nerve on penile biothesiometry. Subsequent neurophysiologic testing in several of these patients has confirmed unsuspected neuropathology. An objective evaluation of autonomic cavernosal neurointegrity is still awaited. Such a test may enable the detection of efferent denervation resulting in neurogenic erectile dysfunction that is not clinically obvious.

Afferent Pathways↗
PubMed1987

Characterization of penile erectile states using external computer-based monitoring.

The states of penile erection have not been quantified to establish their relationship to intracorporal fluid pressure and to soft tissue constraint. Computer-based circumferential rigidity sensing during erectile cycles now permits circumferential size and rigidity characterization. Measurements during dynamic infusion cavernometry and cavernosography relate intracorporal pressure and axial rigidity to circumference and circumferential rigidity characterization. Tumescence/rigidity coupling and tissue elastic contributions are identified from the combined data.

Compliance↗