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Biomedical subjects

H Payer

Publications and source records attributed to H Payer.

15 recordsLinked to original sources
PubMed2002

[Successful topical cyclosporin A in the therapy of progressive vascularising keratitis in keratitis-ichthyosis-deafness (KID) syndrome (Senter syndrome)].

BACKGROUND: The keratitis-ichthyosis-deafness (KID) syndrome (Senter Syndrome) and its major criteria erythrokeratodermia, neuro-sensoric deafness and vascularising keratitis were defined in 1981. Several cases have been described since 1915, but up to now no causal therapy of this disease with sporadic occurrence has been found. Clinical experience using systemic Cyclosporin A (CsA) in the dermatological therapy of the KID syndrome differs. Up to now there has been no report on the use of topical CsA eye drops in the therapy of vascularising keratitis. HISTORY AND SIGNS: We report on a case of keratitis, ichthyosis and deafness (KID syndrome) in a 36-year old male. Both eyes were suffering from recurrent corneal ulcers (ulcus serpens corneae). No improvement had been observed on topical or systemic medication (including lubricants, antibiotics, steroids, etc.) during a history of more than two years. THERAPY AND OUTCOME: Topical CsA 2 % (eye drops, 3 times daily) was administered in addition to lubricants. After 3 months the deep corneal neovascularisations were significantly reduced. The corneal ulcer was closed and visual acuity increased from 20/400 (OU) to 20/100 (OD) and 20/200 (OS), respectively. CONCLUSION: A dose-dependent keratinocyte growth inhibition was found in vitro for cyclosporin A using ichthyosis skin samples. The reduction of activated T-lymphocytes and the resulting reduced HLA-Class-2 expression of conjunctiva and cornea as well as the inhibition of activated T-Cells in the lacrimal gland might be responsible. Nevertheless, the effect of topical CsA on the vascularizing keratitis in the KID syndrome is unknown.

Adult↗
PubMed1989

[Increased episcleral venous pressure in uveal effusion].

This paper reports on two patients with bilateral, spontaneous choroidal and retinal detachment. One patient had scleritis, while in the other no underlying eye disease was found. No signs of orbital venous congestion were detected. Although the pathogenesis of this disease is not fully known, the findings of (1) dilated episcleral veins and (2) elevated episcleral venous pressure suggest an obstruction of venous outflow from the uveal tract. The authors believe that these two findings may have been caused by shunting of venous blood anteriorly from the uveal tract into the episcleral veins due to partial obstruction of the vortex veins.

Aged↗
PubMed1986

[YAG laser iris hole at 6 o'clock in the periphery in the treatment or prevention of closed angle glaucoma and plateau iris and in pupillary block (posterior iris surface-blocking mechanism)].

A shunt between the anterior and the posterior chamber, achieved by shooting an iris hole with a YAG Laser, is presumed to prevent angle closure in eyes with narrow angle glaucoma. Because of their thickening effect on all types of eye tissue, it is advisable to reduce pilocarpine and other miotics once the peripheral iris hole has been created. This is best made at 6 o'clock, since any hemorrhaging caused beneath this point will cease of its own accord. The shunt brings about deepening of the peripheral chamber, and almost always widens the angle in narrow angle glaucoma.

Aged↗
PubMed1985

[Congruent corneal cap of metal foil as protection of the eye against light and heat from operation lamps].

A protective cap of aluminum foil, covering the cornea, offers effective protection from the light and heat of surgical lamps. None of the 120 patients who underwent surgery in the course of a year, for implantation of Siensky-Kratz posterior chamber lenses (Intermedics), developed cystoid macular edema, the protective cap having been used whenever possible during the operation. The glare of the lamps, which is a torture for non-anesthetized patients, should alone be considered reason enough to cover the eye with a protective cap of this kind.

Cataract Extraction↗
PubMed1985

[Circular, small spot argon laser coagulation of the ciliary body band to lower pressure in open-angle glaucoma].

Approximately 100 argon laser coagulations, 50 microns, 0.1 s, 0.5 to 0.8 W depending on pigmentation, performed on the ciliary band in a circular pattern, cause traction on the scleral spur; this causes the inner wall of Schlemm's Canal to become tensioned, preventing collapse and reducing the outflow resistance from the anterior chamber to Schlemm's canal by widening the trabecular meshwork. When use of this method is indicated the results are good in the vast majority of cases. During a follow-up period of between 5 months and 2 years pressure was lowered on average by 7 mm Hg in 95 out of 101 eyes. In 6 eyes a fistulizing operation was necessary to lower pressure to the required level.

Ciliary Body↗
PubMed1983

[Spurred iris hook for implanting posterior chamber lenses of the Kratz, Sinskey and Simcoe types].

The iris hook used for posterior chamber implants (e.g., the Kratz, Sinskey and Simcoe types) has a slight spur at its end. The spur catches the upper loop of the rotating lens during the implantation maneuver and forces it to slide behind the iris. If the spurred hook, retracting the pupil upward, is rotated about 10-15 degrees to the right, it guides the loop more safely and more gently into the posterior chamber. The spur prevents the loop from jerking over the iris hook and back into the anterior chamber.

Humans↗
PubMed1980

[Safety handles for ski sticks to prevent eye, hand and stomach injuries (author's transl)].

Eye injuries caused by ski stick handles are rare but serious. The material and shape of the handle can be designed to prevent serious injury without adversely affecting function. Even at winter temperatures polyurethane remains moderately malleable and shock-absorbent; it is light, and is a poor heat conductor, so that the hands do not get cold quickly. The end of the handle is 8 cm in diameter; attached to this is an adjustable loop which fits around the hand. The loop opens on impact. It is thus impossible for the orbit to sustain injury and there is less danger to other injury-prone regions of the body such as the neck and stomach. The anatomically designed handles, with wide thumb supports, help prevent hand injuries, and in particular thumb injuries, to a large extent. Such injuries have occurred frequently in the past.

Abdominal Injuries↗
PubMed1979

[Trabeculetomy-iridencleisis with marginal cyclodialysis in the treatment of selected cases of childhood- and juvenile glaucoma].

This surgery method is thought for cases, where previous operations have not been successful or for such, in which severe scaring tissue reactions must be expected. The diaphanoscopy of the anterior chamber angle is considered helpfull for the choice of the surgery way. Between 1975 and february 1978 trabeculectomy combined with radical lobelike iridencleisis and marginal cyclodialyse was performed in 4 cases and the i.o. pressure could be normalised. Complications did not occure.

Adolescent↗
PubMed1979

[Results of the 90Sr- and 90Y-radiation after surgical removal of 123 pterygia (author's transl)].

Out of 107 patients 123 pterygia were surgically removed: 24 pterygia of the progressive Type I, 49 of the semi progressive Type II and 50 of the regressive Type III. After surgical removal of the pterygia Type I and Type II followed a treatment with strontium 90 beta radiation with 2700 rep: 900 rep at the 2nd, 8th and 15th day after surgery. The recurrence rate was high in Type I (62%) and Type II (16%), but lower than it is reported in these groups operated without following radiation. More often pterygia of Type I and II are seen in people of the highlands.

Adult↗
PubMed1978

[Trabeculectomy combined with radical lobelike iridencleisis (author's transl)].

Between 1974 and 1977 the new combined operation was performed on 67 eyes with chronic, acute or secondary glaucoma. On observation i.o. pressure was found regulated in all eyes, but 15% needed subsidiary drugs. Complications did not occur more often than in the usual trabeculectomy. In performng surgery it is important to make the canal of Schlemm visible by diaphanoscopy to be sure to include it with the enlarged excision of sclerocorneal tissue. Through the method of excision and radial rupture of the iris lobe the entrance of the sclerociliary tunnel is opened widely. Imbedded iris tissue retards closing of the intended cleft and improves filtration.

Choroid↗
PubMed1978

[Partial palpebral myotarsectomy (author's transl)].

In cases of senile entropium we prefer an operation method, which attempts to exclude the aetiologic factors of these senile alterations. The tension of the tarsus must be increased and the muscle of the orbicularis at the palpebral margin must be reduced and retightened over the convex margin of the tarsus. It is not of less importance to correct the reduced elasticity of the fascia tarsoorbitalis. These corrections are achieved by a perforating rhomboid excision of the lower eyelid. The operation is performed with the use of a Chalazion forceps (Desmarres) which steps all bleeding. The method of operation was successful in all 34 cases and achieved good functional and cosmetic results. Recurrences were not observed.

Entropion↗
PubMed1978

[Trabeculectomy-iridencleisis combined with cataract extraction].

On 31 eyes (23 patients, average age 74 years) with cataract and primary open-angle or chronic angle-closure glaucoma modified trabeculectomy with lobelike iridencleisis was performed combined with cataract-extraction. They were followed up for periods between 6 months and 3 years. In 84% of cases the i.o. pressure continued to be normalized without further antiglaucomatous therapy, in 16% additional treatment with drugs achieved sufficient lowering of i.o. pressure. In nearly all of the cases I observed a diffuse, very flat filtering bleb. Gonioscopy shows, that filtering channels stay open along the margin of the imbedded iris flap. Complications were rare and demanded no further surgery.

Aged↗