Biomedical subjects

H Pockrandt

Publications and source records attributed to H Pockrandt.

At least 19 recordsLinked to original sources

PubMed1984

[Screening for endometrial carcinoma in a group at risk].

In a population-based study 923 asymptomatic women with diabetes aged 40 to 70 years were investigated by aspiration curettage. The samples were evaluated histologically. During the initial screening 4 histologically proved endometrial cancers were diagnosed. All cancer patients were additionally obese and had hypertension, with one exception they were also nulliparous. During the same period the expected number of cases for all investigated women was estimated to 0,74. The expected number of cases limited to those with diabetes, obesity and hypertension was 0,31; and limited to those with diabetes, obesity, hypertension and nulliparity was 0,1, respectively. Additionally 4 cases of adenomatous hyperplasia of the endometrium were identified. The long-term impact on morbidity and mortality of endometrial cancer within the investigated population at risk cannot be assessed as yet.

Adult↗

PubMed1983

[Changes in the vaginal flora caused by supporting pessary treatment in pregnancy].

200 pregnant women with supporting pessary treatment because of cervical insufficiency were compared with one of normal pregnancies concerning microbiological findings and puerperal morbidity. -- 5,5% of the women in the supporting pessary group had pathogenic organisms in their cervix before first amnioscopy, compared to 2% in the control group. The different results of cultural microbiologic examinations in both groups depend on type and duration of birth as well as time of amnion rupture. Women with premature rupture of the membranes (31,0%) had more pathogenic organisms than women with rupture (2,5%) in time. There was no higher infection morbidity compared to the control group.

Female↗

PubMed1982

[Oestradiol receptors in endometrial carcinomas (author's transl)].

Tissue samples taken from endometrial carcinomas as well as from normal and hyperplastic endometria were tested for oestradiol receptors. Roughly one and the same amount of receptors was recordable from all three tissue groups. In premenopausal women, receptor levels were lowest in the advanced phase of secretion. All tumour patients so far have survived without recurrence. Therefore, no correlation has been established, as yet, between receptor level and prognosis, in a way similar to what has been found in cases of mammary carcinoma.

Adult↗

PubMed1981

[Risk group oriented early detection of cervical cancer? (author's transl)].

In a retrospective case-control-study 500 women with a carcinoma in situ of the cervix uteri and 500 controls were examined by a standardized interview and compared by matched pair analysis. 8 risk factors for ca in situ were found indicating a lower social status, earlier sexual activities and more frequent inflammations of the cervix uteri. However screening programs should not be restricted to such women because it is difficult and expensive to identify and to reach the high risk group.

Carcinoma in Situ↗

PubMed1979

[On the therapy of uterine cervix carcinoma in situ].

It is reported of 607 cases of uterine cervix carcinoma in situ from the years 1963 to 1977. During this period, the diagnostic and therapeutic procedures as well as the histological preparation technique have advanced. -- 75% of the cases were primarily conized. About half of these cases were surely radically excised. 323 patients (53,2%) were treated actively by simple hysterectomy, 242 patients (46,8%) were treated conservatively (190 conisations, 19 reconisations, 60 portioamputations, 12 ringbiopsies, 3 radiations). -- After 323 total exstirpations, 2 recurrences of carcinoma in situ in vaginal stump were observed (0,6%). After local treatment of 242 patients, 17 recurrences of the disease appeared (6%), among them 4 cases as invasive cervix carcinoma. 11 cases belong to the group of primarily nonexcised or uncertainly radically excised carcinoma in situ, and in 4 cases a possibility of recurrence has been discussed. -- It has been refered to the importance of the exact conisation technique and subtile histotechnical obtaining of slides in step sections. If the carcinoma in situ radically excised and followed by an attentive follow up in women below 40 years, a conservative procedure is adviced. For women above 40 years an active procedure is indicated, because it offers a high therapeutic reliability and a minimal risk. For cases of nonradically excised carcinoma in situ hysterectomy is indicated. The removal of the vaginal cuff is considered as unnecessary.

Adult↗

PubMed1978

[Results of directed cytoctatic therapy for ovarian cancer].

The paper presents the comparison of the results of individualized postoperative chemotherapy and non-individualized treatment with Trenimon in ovarian cancer patients. Individual treated patients had a mean survival time of 9.7 months and the other group only 9.4 months, that means, there are no significant differences between the two treatment groups.

Antineoplastic Agents↗

PubMed1975

[Results of preventive mycological examination in pregnant women].

From accidential patients fifteen per cent of 2328 pregnant women showed in a cultural method (malt-extract-agar) a vaginal mycosis in the seventh month of pregnancy. In most of the cases it was Candida albicans, but there were also other cases of Candida and Toruplopsis glabrata. The therapy of vaginal mycosis during pregnancy should be done generally, to prevent infections of infants and infections is gynecological and neonatological departments.

Antifungal Agents↗

PubMed1975

[1st results with a new suction curettage system].

The point is a self-developed Suction-curette-system, consisting of a suction-curette of diametres of 3, 4, 5, 6, 7 und 8 mm, a cervicometer and a filter. Effectivity and histological evidence of 1. Suction-curettage after hysterectomy 2. Suction-curettage before hysterectomy in full-narcosis 3. Suction-curettage without full-narcosis were examined. Advantages of this method are discussed.

Adult↗

PubMed1975

[Medical evaluation and rehabilitation following intensive therapy of malignomas in the female genitalia and breast].

The selective therapy of malignant tumours of the female genital tract has led to the abandonment of radical procedures in the treatment of early stages of carcinomas. The histological diagnosis, including tumour localisation, tumour grading, applied therapy, early and late complications are criterion to be taken into consideration in laying down the degree of infirmity. In the light of functional gynaecology, principles for such patients care are laid down, taking into account the time of disablement as well as problems of rehabilitation, not only for patients with malignant tumours of the female genitals but for those with mammary tumours as well.

Aftercare↗

PubMed1974