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Biomedical subjects

H Prange

Publications and source records attributed to H Prange.

7 recordsLinked to original sources
PubMed1979

[Acute renal failure in alcoholic myopathy (author's transl)].

Two chronic alcoholics developed acute renal failure from alcoholic myopathy (acute alcohol-induced rhabdomyolysis). Severe muscle pain developed and was associated with transitory oligo-anuric renal failure, requiring dialysis in one patient. In addition to the typical history and clinical symptoms, excessive elevation of muscle enzymes, especially creatine-kinase, and the appearance of myoglobin in serum are characteristic. Brown discoloration of the urine and a falsely positive test for "blood" due to the presence of myoglobin in urine in the absence of red blood cells are also typical. Definite changes can be demonstrated histologically and electromyographically during the acute stage. It is likely that this condition is more frequent than the sparsity of published reports indicates.

Acute Kidney Injury↗
PubMed1979

[Pathomorphological changes in the skeletal muscles (musculus longissimus dorsi) in swine following varied transport stresses and resting periods prior to slaughter].

The M. longissimus dorsi of 171 pigs were histologically examined for pathological signs. Acute hyaline-plaque degenerations and necrosis (hsD/N) in various degrees of manifestation were recorded from 42.7 and hyaline transverse ligaments (hQb) from 22.8 per cent of all cases. The occurrence of hsD/N following container transport was lower with significance (33.3 per cent) than that following lorry transport (50.5 per cent). The form of transport failed to have any substantive effect on the occurrence of hQb, the figures being 20.5 per cent for container and 24.7 per cent for lorry. Short resting periods, between 0.5 and 1.2 hours, were followed with significantly higher occurrence of hsD/N, as compared to longer resting periods, between five and eight or 23 hours. These pathological findings were not further reduced by extending the resting period from something between five and eight to 20 hours. The pathological hsD/N and hQb findings were recordable from both PSE pork (hsD/N = 51.4 per cent, hQb = 25.7 per cent) and from pork without any quality shortcomings (hsD/N = 39.7 per cent, hQb = 22.1 per cent), but the number of hsD/N cases in the context of PSE pork tended to be higher than that in high-quality pork. No sex dependence was established. The results are discussed under the aspect of aetiopathogenesis of stress-borne myopathy.

Animals↗
PubMed1977

[Muscle meat quality in swine. 4: Response of fattening pigs to removal from pigsty and transport to slaughterhouse].

Blood was sampled through indwelling catheters from pigs taken to places for slaughter by various means of transport. Sampling took place at different measuring points between removal from pig pens and actual slaughter. The blood was tested for haemoglobin, haematocrit, glucose, and lactate. The following results were obtained: Removal and transport led to strong Hb and medium Hk rises. The levels, however, returned to normal after one-and-a-half to two hours rest. Stresses caused prior to and during anaestheria led to considerable rise of Hk and Hb as well as to maximum lactate deflection. The latter excitations superimposed all the preceding reactions of the organism. The increased of Hb, Hk, and lactate recorded from animals slaughtered as little as 20 minutes after arrival were higher than those established from animals that had been allowed some rest in between. Transport losses were reduced when the animals were moved in containers due to less motoric stress. However, no mitigation of pork quality setback can be expected as long as strong excitation continues to be caused in the animals before slaughter.

Abattoirs↗