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Biomedical subjects

H Price

Publications and source records attributed to H Price.

At least 37 records · Page 2Linked to original sources

Psychosocial aspects of cardiac pacing.

The psychosocial effects of pacemaker implantation were analysed in 96 randomly selected patients receiving their first pacemaker at the Johannesburg General Hospital from August 1976 to December 1977. Premorbid personality together with emotional acceptance of the pacemaker was assessed by a social worker at interviews before implantation and 3 months and 1 year after implantation. Depression was measured by the Hamilton rating scale, and a psychosocial history was taken from each patient. The nature and severity of symptoms and associated diseases were assessed medically. Pacemaker implantation restores most patients to occupational, social, emotional and physical usefulness. The degree of relief of symptoms played an important part in rehabilitation. Inadequate adjustment and rehabilitation may occur in the presence of additional disease, unrealistic patient expectations, an inadequate, depressive personality type, poor doctor-patient communication, or in patients who have experienced symptoms for less than 1 month before the implantation. Adequate pre-operative preparation by a team of social workers and doctors together with public education and the provision of postoperative psychosocial support for the inadequate, depressive personality type and for patients suffering from additional disease is likely to enhance rehabilitation greatly.

Adult↗

An analysis of 113 intracranial infections.

The location, source of infection, and CT characteristics of 90 intracerebral abscesses and 23 subdural empyemas are reported with special regard to capsule enhancement and surrounding cerebral edema.

Adult↗

The urographic signs of acute on chronic obstruction of the kidney.

The signs of acute obstruction of the kidney and of chronic obstruction are well recognised and the combination of these signs enables a group of patients with acute-on-chronic obstruction to be recognised. The signs of acute obstruction are entirely nephrographic. They are manifested by an increasingly dense nephrogram, which may become striated, followed by an anatomically normal pyelogram. The signs of chronic obstruction are both pyelographic and nephrographic. The pyelographic signs are a dilated pelvicalyceal system. The nephrographic signs are a normal or low density nephrogram. Crescents may appear; these are due to opacification of the distorted medulla which retains its ability to concentrate the urine. In acute-on-chronic obstruction the signs of both conditions are present. Thus there is an increasingly dense nephrogram with a negative pyelogram. Crescents may appear. There is a slow flow in the dilated pelvicalyceal system.

Acute Disease↗

The evaluation of head trauma by computed tomography.

A retrospective study of 133 patients with documented head trauma is presented. Computed tomography (C.T.) has replaced cerebral angiography in the evaluation of these patients at our institutions. C.T. provides a rapid noninvasive diagnosis, plus accurate localization of lesions; it also allows for the assessment of multiple lesions. The authors feel that C.T. should be the first neurological mode of investigation after plain skull radiographs. It is important to obtain good quality scans, and intravenous sedation or general anaesthesia may be required.

Brain Abscess↗

Breast-milk monitoring to measure Michigan's contamination with polybrominated biphenyls.

In 1973 and 1974, several thousand Michigan dairy farms were contaminated by polybrominated biphenyls (P.B.B.) as the result of an industrial accident. An unknown quantity of contaminated meat and dairy products entered the food chain before contaminated farms were quarantined. To determine the extent of human exposure, P.B.B. concentrations were measured in human breast milk, which was collected in a random-sample survey from nursing mothers throughout Michigan. 96% of 53 samples from Michigan's lower peninsula and 43% of 42 samples from the less densely populated upper peninsula contained detectable levels of P.B.B. These data indicate that about 8 million of Michigan's 9.1 million residents have detectable body burdens of P.B.B.

Accidents, Occupational↗

The Abortion and Sterilization Act in 1975--experience of the Johannesburg Hospital Pregnancy Advisory Clinic.

The experience of a Pregnancy Advisory Service operating in terms of the Abortion and Sterilization Act of 1975 is reviewed. A total of 454 applications for abortion were considered, of which 198 (44%) were accepted and the abortions performed. The urgent need for sex education at schools, colleges and universities is stressed, in view of the large number of scholars and students under the age of 17 who seek an abortion. There are also patients who discontinue contraception for a variety of reasons, on medical advice or otherwise, without an alternative being suggested or sought. Motivation of patient, nurse and doctor needs urgent improvement.

Abortion, Legal↗

The role of computerised tomography in the diagnosis and management of intracranial abscess.

A retrospective study has been undertaken of patients with intracerebral abscess and subdural empyema. Computerised tomography (CT) offers a rapid, non-invasive mode of diagnosis with accurate localisation and assessment of multiplicity of lesions. We propose that early diagnosis and correctly timed surgical intervention has lessened the mortality rate. CT allows for easy follow-up of patients and has allowed us in one case, to treat an inaccessible abscess conservatively.

Adolescent↗

Structures of gangliosides from bovine adrenal medulla.

Five gangliosides, accounting for over 95% of the total ganglioside fraction, were isolated from bovine adrenal medulla by preparative thin-layer chromatography and the carbohydrate structures determined by a combination of periodate oxidation and permethylation techniques. Partially methylated alditol acetates were generated from the neutral sugars of the fully methylated glycolipids and identified by gas-liquid chromatography. Substitution on N-acetylgalactosamine was determined by methanolysis of the permethylated ganglioside, acetylation of the products, and identification of the resulting substituted methyl glycosides by GLC. Periodate oxidation followed by borohydride reduction confirmed some of the linkages and demonstrated the absence of (2-8) linkages between sialic acid units. Mass spectrometry of the permethylated gangliosides gave information on sugar sequence at the nonreducing end.

Adrenal Medulla↗