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Biomedical subjects

H Quaynor

Publications and source records attributed to H Quaynor.

7 recordsLinked to original sources
PubMed1995

Frequency and severity of headache after lumbar myelography using a 25-gauge pencil-point (Whitacre) spinal needle.

We studied 63 patients between the ages of 20 and 81 years undergoing lumbar myelography, using a 25-gauge pencil-point (Whitacre) spinal needle. With the use of a questionnaire, the incidence and severity of post-dural-puncture headache (PDPH) was investigated. There were three patients who complained of PDPH (4.7%), two of whom described their headache as moderate and one as mild on a visual analogue scale. All the headaches were alleviated by mild analgesics and no patient experienced severe headache needing treatment with a blood-patch. There were three other patients who experienced a post dural-puncture-related headache which, unlike PDPH, was not postural. Four patients had ordinary mild headache. The quality of the myelograms was good.

Adult↗
PubMed1993

Classification and severity of postdural puncture headache. Comparison of 26-gauge and 27-gauge Quincke needle for spinal anaesthesia in day-care surgery in patients under 45 years.

Two hundred and five patients, aged 16-45 years, undergoing day care surgery were given a spinal anaesthetic using either a 26- or a 27-gauge Quincke point spinal needle. The occurrence of headache and accompanying symptoms postoperatively was analysed from 186 returned questionnaires. The incidence of classical postdural puncture headache was 4.5% following the use of a 26-gauge needle and 8% with a 27-gauge needle (p > 0.05). A further group of patients suffering headache after dural puncture was identified, the postdural puncture-related headache. The headache and accompanying symptoms were similar to that seen with a postdural puncture headache except that it was not aggravated by posture. A system of grading the severity of both type of headache is presented and standardised criteria for the classification of postdural puncture headache are proposed.

Adolescent↗
PubMed1990

Spinal anaesthesia in day-care surgery with a 26-gauge needle.

We studied 106 day-care surgical patients (52 male) aged 18-70 yr (mean 49.6 yr) who received spinal anaesthesia with a 26-gauge spinal needle. The incidence of headache, back pain and patient acceptability were investigated after operation using a questionnaire. The incidence of postspinal headache was 7.5%, and 11.3% of patients developed back pain. One patient remained in hospital because of hypotension and dizziness. There were no major complications and patient acceptability was almost 100%. We conclude that spinal anaesthesia for day-care surgery is easy to perform and cost effective.

Adolescent↗
PubMed1987

Pharmacokinetics of i.v. and rectal methohexitone in children.

The pharmacokinetics of methohexitone were investigated in 15 healthy children undergoing minor surgery under inhalation anaesthesia. Six received 1% methohexitone 1-2 mg kg-1 i.v. and nine received 10% methohexitone 20-25 mg kg-1 per rectum. On i.v. administration, three-compartment pharmacokinetics generally applied. The mean elimination half-life of methohexitone was 193 +/- 75 min; that is, considerably longer than previously reported for children, but in good agreement with findings in adults. The mean clearance was 17.9 +/- 8.3 ml min-1 kg-1, the volume of distribution at steady state was 2.1 +/- 0.24 litre kg-1 and the mean residence time was 134 +/- 47 min. The pharmacokinetic model used for the i.v. data was easily modified to suit the plasma concentration curves obtained on rectal administration. The mean bioavailability of methohexitone administered per rectum was 17%, with a six-fold variation between individuals.

Administration, Rectal↗
PubMed1985

Extradural blood patch--why delay?

Seven patients are described in whom a prophylactic blood patch was instituted within 15 min of accidental dural puncture. Five of the patients received extradural anaesthesia before the blood patch, and one after the blood patch had been performed. In three of these patients further "top-up" doses of local anaesthetic were performed through the extradural catheter. The quality of analgesia obtained was satisfactory. No symptoms of spinal headache occurred in any of the patients.

Adult↗
PubMed1985

Rectal induction of anaesthesia in children with methohexitone. Patient acceptability and clinical pharmacokinetics.

Rectal induction of anaesthesia with 10% methohexitone 100 mg ml-1 was used in 50 healthy children, using a standard dose of 25 mg/kg body weight. The absorption of methohexitone was rapid and reliable: the children fell asleep within 10-15 min. The plasma concentration peaked at 10-15 min and then decayed rapidly. The terminal half-life of rectal methohexitone was 1-2 h. Overall patient acceptability was good, and there were no major complications.

Anesthesia, Rectal↗