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Biomedical subjects

H R Degryse

Publications and source records attributed to H R Degryse.

At least 19 recordsLinked to original sources
PubMed1996

Unusual presentation of ovarian pathology on CT.

A prospective study including seventy-seven consecutive patients suspected of having ovarian tumoral or pseudotumoral pathology on CT was carried out. Fifty-nine patients had surgery with histological diagnosis. When comparing the CT and histological findings in benign and malignant lesions we obtained an overall accuracy of 95% with only three misdiagnosed cases on CT. False positive diagnosis of malignancy was established in a case of abdominal actinomycotic infection, a case of chronic appendicitis, and in a ruptured ectopic pregnancy. These three cases are discussed in detail.

Adult↗
PubMed1994

Randomised double blind trial of the safety and efficacy of two gadolinium complexes (Gd-DTPA and Gd-DOTA).

The main difference between macrocyclic Gd-DOTA and linear Gd-DTPA complexes is the greater stability of the former which theoretically might reduce biological interactions in man. To evaluate the clinical relevance of this property, 300 unselected neurological patients were included in a randomised double-blind comparison involving five European centres, focused mainly on the tolerance of these two contrast media. Clinical tolerance was assessed immediately after the procedure and 24 h later. Adverse events were found with a similar frequency in the two groups (17.3% for Gd-DOTA and 19.3% for Gd-DTPA). Minor neurological symptoms were the most frequent (48.6%) headache being the most common (29.2% of adverse events). No difference in efficacy was found.

Adult↗
PubMed1993

Acoustic schwannoma: MR findings in 84 tumors.

MR imaging is the study of choice for the examination of patients with suspected acoustic schwannoma, because of its high sensitivity, especially after the use of contrast material. This essay illustrates the common MR features of acoustic schwannomas as seen in a study of 84 tumors. We pay special attention to the role of MR imaging in the distinction between acoustic schwannoma and meningioma.

Adolescent↗
PubMed1992

Statistical analysis of MRI parameters predicting malignancy in 141 soft tissue masses.

Since well-known grading parameters such as cellularity, mitotic rate, matrix and presence of necrosis all influence MRI signal intensity, the value of MRI in predicting malignancy is potentially high. To assess this value we studied retrospectively the findings in 141 soft tissue tumours (84 benign, 57 malignant) and evaluated a wide variety of MRI features (size, margins, signal homogeneity, shape, signal intensity, neurovascular and bone involvement, degree and pattern of enhancement and evidence of necrosis after injection of Gd-DTPA). Statistical analysis was carried out to determine accuracy of parameters individually and in combination, for predicting malignancy. Highest sensitivity was obtained for "absence of low signal intensity on T2" (100%), "mean diameter greater than 33 mm" (90%), and "inhomogeneous signal on T1" (88%). Highest specificity was obtained for "evidence of necrosis" (98%), "bone or neurovascular involvement or metastases" (94%), and "mean diameter greater than 66 mm" (87%). Association of best sensitivity and specificity was seen for "absence of low signal intensity on T2", "signal inhomogeneity on T1", and "mean diameter of the lesion greater than 33 mm" (81 and 81%).

Adolescent↗
PubMed1992

Magnetic resonance imaging of soft tissue tumors.

The value of magnetic resonance imaging (MRI) in histological classification was studied in a series of 164 histologically proven soft tissue tumors (STT) and was rather limited. MRI was only valuable in characterization of lipomatous, vascular and fibrous tumors. There are two main reasons for this limitation i.e. STT belonging to the same histological group may have different composition or different proportions in tumor components resulting in different MRI signals. Secondly tumor components may change individually or proportionally during natural evolution or as a consequence of therapy. Because well known grading parameters such as cellularity, mitotic rate, matrix and presence of necrosis all influence MRI signal intensity, the value of MRI in predicting malignancy is potentially high. To assess this value we retrospectively studied the findings in the first 141 soft tissue tumors (84 benign, 57 malignant) and evaluated a wide variety of MRI features (size, margins, signal homogeneity, shape, signal intensity, neurovascular and bone involvement, degree and pattern of enhancement and evidence of necrosis after injection of Gd-DTPA). Statistical analysis was carried out to determine accuracy of parameters individually and in combination, for predicting malignancy. Highest sensitivity was obtained for "absence of low signal intensity on T2" (100%), "mean diameter > 33 mm" (90%) and "inhomogeneous signal on T1" (88%). Highest specificity was obtained for "evidence of necrosis" (98%), "bone or neurovascular involvement or metastases" (94%) and "mean diameter > 66 mm" (87%). Association of best sensitivity (81%) and specificity (81%) was seen for "absence of low signal intensity on T2", "signal inhomogeneity on T1" and "mean diameter of the lesion > 33 mm". In a prospective study of 23 consecutive patients we reevaluated sensitivity and specificity in predicting malignancy of all parameters. Excellent correlation with the results of the retrospective study was found. Although a quantitative approach to the staging potentials of MRI was not possible, well known staging parameters are evaluated to the best by this method (size, depth, compartmental versus extra-compartmental location, relationship to adjacent structures).

Adolescent↗
PubMed1992

Magnetic resonance imaging of extraabdominal desmoid tumors.

The authors describe the MR appearance of extra-abdominal desmoid in three patients, with longitudinal follow-up during a period of up to 29 months in two of them. For the MR examinations various pulse sequences, including spin-echo and gradient-echo sequences, were used. Both non-enhanced and Gd-DTPA contrast enhanced studies were made. We found gradient-echo T2*-weighted sequences best suited for the detection of extra-abdominal desmoids. Best correlation between MR features and histologic findings was obtained on spin-echo T2- and contrast enhanced T1-weighted studies. Although preliminary, our results suggest that MRI might predict evolution of extra-abdominal desmoids by providing data about cellularity and relative amount of mucoid matrix of the lesions.

Adult↗
PubMed1991

Calcific tendinitis of the vastus lateralis muscle. A report of three cases.

Three cases of calcific tendinitis occurring at an unusual site (vastus lateralis tendon) are described. Findings on conventional radiography and computed tomography together with the clinical history are characteristic for this disorder and reflect its natural evolution. The actual role of magnetic resonance imaging seems limited to excluding neoplasm and to demonstrating inflammatory changes better in the early stages of disease.

Aged↗
PubMed1991

Polypoid hamartoma of the jejunum.

The authors report an unusual case of jejunal mesenchymal hamartoma which presented as a bleeding pedunculated polyp in a 67-year-old woman. The lesion was detected by enteroclysis and resected after localization by intraoperative endoscopy.

Aged↗
PubMed1990

Herpes simplex virus type 1 colitis: an unusual cause of diarrhea.

Herpetic infections of the gastrointestinal tract are a well-recognized entity. Involvement of the colon seems to be very rare. A 78-yr-old woman developed bloody diarrhea and abdominal discomfort 2 months after surgical treatment for adenocarcinoma of the transverse colon. Colonoscopy revealed diffuse hemorrhagic, erosive, aphtoid, and ulcerative lesions. Histology showed nonspecific inflammatory changes. Herpes simplex virus type 1 (HSV-1) was isolated from endoscopic biopsy and stool specimens. The patient responded rapidly to symptomatic treatment with loperamide. This case demonstrates the potential for HSV-1 to induce infectious colitis; failure to obtain microbiologic evaluations and the rapid response to empiric, symptomatic treatment may be responsible for the rarity of diagnosis of this infection. The implications of this diagnosis are probably more relevant in immunosuppressed individuals, and may be important in the elderly population.

Aged↗
PubMed1989

Magnetic resonance imaging in the evaluation of patients with eosinophilic fasciitis.

Two cases of eosinophilic fasciitis are described, in which magnetic resonance imaging (MRI) clearly demonstrated thickening of the fascia and increased signal intensity in the superficial muscle fibers correlating with inflammation. MRI is a useful noninvasive imaging technique in the diagnosis of eosinophilic fasciitis and can guide biopsy of selected abnormal areas.

Biopsy↗
PubMed1987

Computed tomography of the polysplenia syndrome in the adult.

The computed tomographic appearance of the polysplenia syndrome in 2 cases is presented. Both are associated with absence of the hepatic segment of the inferior vena cava. Computed tomography can determine the exact location of the malpositioned organs, the presence of multiple spleens, and the type of the associated venous anomalies, which are the major features of the polysplenia syndrome.

Abnormalities, Multiple↗