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Biomedical subjects

H R Harley

Publications and source records attributed to H R Harley.

9 recordsLinked to original sources

Congenital broncho-oesophageal fistula in the adult.

The case of a 46-year-old man with congenital broncho-oesophageal fistula is presented. The patient had had recurrent chest infections since childhood and a recent history of heartburn and flatulence. A barium-swallow examination showed a small sliding hiatal hernia and an oesophageal diverticulum communicating via a fistula with the apical and posterior segmental bronchi of the left lower lobe. Bronchography showed bronchiectasis in this lobe. At thoracotomy resection of the broncho-oesophageal fistula and left lower lobectomy were performed. The patient's recovery was uneventful. Twenty published cases are reviewed. The classification of congenital broncho-oesophageal fistulae should take account not only of the type of fistula but also of the type and size of the bronchus with which the fistula communicates, the age of the patient at the first appearance of symptoms, and the duration of symptoms.

Bronchial Fistula↗

Cancer of the lung in women.

A study from Wales of 132 women with cancer of the lung admitted consecutively during the five years 1964-68, and of 13 other women submitted to surgery at an earlier period, showed that the prognosis for women was worse than for men. Every woman except one was followed up for more than five years. Of the 132 women in the consecutive series only five survived for five years, while the five-year survival rate after resection in 35 women was less than one-half of that of men. The cause of the worse prognosis for women in Wales appears to be due to some sex-linked factor. It cannot be explained by the age of the patient or by the histology, location, early or resectability of the growth. The prognosis of cancer of the lung in English, French, and American women is considered. The relative incidence of the disease in women and men is discussed. Sex and nationality appear to be of importance, but the influence of tobacco and other atmospheric carcinogens is obscure.

Adenocarcinoma↗