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H R Klein

Publications and source records attributed to H R Klein.

10 recordsLinked to original sources
PubMed1982

Actions of antidepressant and neuroleptic drugs on ACTH- and novelty-induced behavior in the rat.

The present study deals with the effects of psychoactive drugs (neuroleptics and antidepressants) on ACTH-induced excessive grooming in the rat. The neuroleptics haloperidol and clozapine and the antidepressants amitriptyline, nomifensine and mianserin all suppressed the grooming response in a dose-dependent manner. The neuroleptic sulpiride was ineffective even at high doses. Experimental evidence is presented suggesting that the suppression of peptide-induced grooming was not the result of competing behavioral activity elicited by the drug itself. Instead it is assumed that the psychoactive drugs tested affected directly the activity of the neural substrate underlying the peptide-induced behavior. In view of the complexity of the mechanisms of action of the drugs tested it is argued that this substrate may be a more complex one than the dopamine systems as suggested before.

Adrenocorticotropic Hormone↗
PubMed1979

[Phase coordination between maternal and fetal heart rhythm during pregnancy (author's transl)].

In pregnant women during 8th and 9th month of pregnancy simultaneous registrations of the maternal and the fetal electrocardiograms were carried out, generally by systematic long-term studies during night rest. It could be proofed by examinations of the frequency distribution of the maternal R-peaks within the fetal cardiac cycle as well as of the frequency distribution of the fetal R-peaks within the maternal cardiac cycle that around a whole number frequency relationship of both of the heart rhythms a phase coordination between maternal and fetal heart actions occurs, leading to a preference of a defined phase relationship. According to the detected phase relationship it can be presumed, that the fetal rhythm is triggered by the guiding maternal pulse wave rhythm within a small range.

Electrocardiography↗