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Biomedical subjects

H Rüttgers

Publications and source records attributed to H Rüttgers.

At least 19 recordsLinked to original sources
PubMed1979

[Investigation of the epidemilogy of fungal vaginitis in 1000 patients (author's transl)].

In the out-patient department and antenatal clinic 1000 patients were examined for yeast of the genital tract by the nickerson-medium. In 10.3% of the patients the cultures showed yeast. The wet-mount preparation examination under phase contrast microscopy was compared to the nickerson-medi-m culture. Patients with a past history of yeast infections or patients with an intrauterine device showed a statistically significant increase in the rate of yeast vaginitis compared to the control groups. Patients who had antibiotics or were treated with corticosteroids showed a higher incidence of yeast vaginitis than normal controls. Controls had a 9% incidence. The number of cases was too small for statistical analysis. The incidence of yeast vaginitis in patients on combined or sequential oral contraceptives was the same as in the control groups. The pregnant patients and obese patients did not show an increased incidence of yeast. High risk patients for yeast vaginitis are defined in which a culture for yeast is jusitfied. Especially antenatal patients in the last trimestre are a high risk group because of the possibility of neonatal thrush.

Adolescent↗
PubMed1978

Influence of sterilization and temperature changes on the in vitro characteristics of the pH electrode.

1. When chemical sterilization (with Korsolin, Cidex) is performed, a minimal duration of sterilization of 3 h is required for asepsis. 2. Duration of Korsolin sterilization up to 3 h does not influence the in vitro characteristics of the pH-electrode. 3. Sterilization with formaldehyde (24 h, 40 degrees C) is safe, but needs another 24 h restabilization time of the electrode. 4. The temperature dependence of the pH-electrode is minimal. With increasing temperature a slight decrease of pH measurement can be found (-0.02 pH units from 20--40 degrees C).

Disinfectants↗
PubMed1978

In vivo performance of the pH tissue electrode during acute acid-base changes in the dog.

The ROCHE tissue pH-electrode was tested in acute animal experiments under various metabolic conditions. In anesthetized dogs an electrode was placed in the subcutaneous tissue of the scalp, neck, and axilla. Simultaneous with the continuous measurement of tissue pH, the overall acid-base balance of the animal was measured discontinuously at 5-min intervals by means of indwelling arterial and venous catheters. Various forms of acidosis and hypoxia were produced in the experimental animal and the sensitivity of the electrodes in relation to their site was tested. A high correlation between the continuously measured tissue pH values and the corresponding arterial and venous actual blood pH values were found in the physiologic pH range. With acute changes of acid-base balance no correlation could be found in the acidotic range.

Acid-Base Imbalance↗
PubMed1978

A new application tool for the ROCHE pH electrode.

Using this tool the application of the pH electrode is nearly as easy as the attachment of a common ECG-scalp-electrode [3]. Visual control and lithotomy position is not necessary any more. The different tools are adapted to each other so that incision place and the tip of the pH electrode are automatically centered perpendicularly. The first results by using this tool promise to be successful. Time of application is short, the maintenance of the pH electrode is good and the application for the patient no longer disagreeable.

Electrodes↗
PubMed1978

Continuous measurement of tissue pH in the human fetus.

The ROCHE pH electrode was tested clinically in 20 fetuses and one nonviable newborn with severe malformations. The proper fixation of the electrode in the fetal scalp is difficult. In the physiologic pH range a good correlation between capillary blood pH and tissue pH exists. The situation is less clear for the acidotic range.

Capillaries↗
PubMed1977

[The inhibition of prostaglandin induced uterine contractions by diazoxide in vitro (author's transl)].

The tocolytic efficiency of Diazoxide, a benzothiadiazine derivative with pronounced musculotropic action, was tested on the isolated uteri of non-gravid and gravid rats. Regular uterine contractions were induced by the prostaglandines E2 and F2 alpha. Their amplitude and frequency could be suppressed totally or subtotally. Contraction intervals lasted 4--22 min. The basal tone was reduced in most cases.

Animals↗
PubMed1976

[The inhibition of spontaneous and oxytocin-stimulated uterine contractions in isolated rat uteri with diazoxide (author's transl)].

Diazoxide, a benzothiadizin derivative without diuretic effect, was tested for its tocolytic effectiveness in isolated uteri from pregnant and nonpregnant rats. Amplitude, frequency, basal tonus and duration of the total inhibition of labor pains were interpreted as parameters. Total or subtotal inhibition of amplitude and frequency could be obtained in all experiments. The duration of total inhibition of labor pains was between 3 and 27 minutes. Affect on the basal tonus was not consistant.

Animals↗
PubMed1975

Significance of amniotic fluid phospholipid determination for the prediction of neonatal respiratory distress syndrome.

198 amniotic fluid samples, obtained from 14-42 weeks of 158 patients were assessed for amniotic fluid phospholipids (total phospholipids, lecithin, sphingomyelin, lecithin/sphingomyelin ratio). The TPLP and Lec-concentrations show significant rises in concentration after 34th week whereas the sphingomyelin concentration remains virtually constant during pregnancy. L/S ratio remains relatively constant smaller than or equal to 2 prior to 32 weeks and smaller than or equal to 3 between 32 and 34 weeks but shows then a steep rise. The amount of Lec (expressed as percentage of total phospholipid concentration) rises from 30-40% at 30 weeks to 70-80% at term whereas the amount of Sph declines from 30-40% to less than 10%. In 12 cases neonatal RDS occurred. With L/S ratio treshold values of 3 correct prediction of RDS was made in 83% of cases, whereas probability of RDS occurrence was 63%. With L/S ratio values greater 3 RDS can be excluded in 95% of cases. The corresponding figures for Lec and TPLP concentration are described too. The range of different results in the literature is discussed.

Amniocentesis↗