[Meeting of the Scientific Medical Society of Gynecology and Obstetrics of the Dresden and Cottbus district 25 May 1990 in Cottbus].
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Biomedical subjects
Publications and source records attributed to H Radzuweit.
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Based on a multicentric prospective study 727 cases of caesarean section (C.S.) in 13 departments of gynecology and obstetrics in 1987 will be examined by means of computer aided analysis. The rate of C.S. was between 6.5% and 13.4% in the obstetrical centres, and between 2.6% and 6.7% in the general district hospitals. There isn't a defined correlation between the rate of C.S. and perinatal mortality in one department. The increased C.S. rate of the centres is based on more neonatological indications like prematurity, perinatal infection risk and traumatic hazard. Perinatal mortality and C.S. rate are only comparable under consideration with all cases of deliveries especially with frequency of obstetrical high risk cases in a department. The high C.S. rate of first obstetrical centre in comparison with the second one is connected with reducing of perinatal mortality of newborn delivered by C.S. to about the half. Therefore we suggest the caesarean section-index of perinetal mortality. It is the relation between perinatal mortality of newborn delivered by C.S. and the total perinatal mortality.
In order to get evidence about the incidence of malformations as because of intrauterine exposition of steroids as after cessation of hormonal contraception in dependence on the time interval between the last intake of hormonale contraceptives (h.c.) and on different pills 5,866 pregnant women have been entered into a case-control-study. 2,834 pregnant women had taken h.c. during pregnancy or got pregnant within 6 menstrual cycles after discontinuation of pills (= cases). For control the data of 3,032 pregnant women were examined. These one had never taken pills or their pregnancy occurred after 7 menstrual cycles after cessation of pill ingestion. Perinatal mortality, Apgar-score (5 min) and incidence of twins were not different in cases and controls. The incidence of malformations was significant (p less than or equal to 0.01) higher in controls than in cases. It depended on age in form of an increase with rising age. The incidence of malformations in both groups increased significantly (p less than or equal to 0.01) with a rising cigarette consumption during pregnancy. The results of this study suggest that smoking regarding malformations represents a higher risk than the intake of h.c.
Appendectomy was performed on 34 pregnant women between 1977 and 1984. These accounted for 1.1 per cent of appendectomies and 1.8% of all deliveries in the above period under review. The incidence of appendicitis during pregnancy did not appear to be very much below that outside gravidity. The foetus is endangered by hypoxaemico-toxic conditions in all phases but primarily during the last three months. Caesarean section should be precedent to appendectomy, at least in cases of advanced appendicitis and when the foetus is viable. With non-viable foetus, appendectomy should be performed alone.
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More seldom allergic patients suffer from cancer than healthy ones. The level of serum-IgE of these patients is higher whereas IgE of cancerous patients is often lower. 16 patients with gynaecologic cancer and without allergic anamnesis were examined and the results were compared with references in literature. A possible importance of IgE for the physical prevention against tumor is being discussed.
A reproducible method for the determination of bilirubin in amniotic fluid by measuring the extinction of the the chloroform extract is described. The measurements can be carried out by means of a simple spectrophotometer. In case of extraction of amniotic fluid containing blood informative results are obtained as well. Since the extinction values are equal to the deltaE-values it is possible to determine the degree of morbus haemolyticus fetalis using the schema of Liley.
The present paper is intended to assess the amount of fetomaternal transfusion in the first and second half of pregnancy, in the peripartal phase as well as in abortion and interruption. The findings of our investigations show that the obtained values of HbF cell invasion approximately correspond to the invasion values in the postpartal phase and call for general immunoprophylaxis in Rh-negative women.