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H Rebscher

Publications and source records attributed to H Rebscher.

10 recordsLinked to original sources

Complexities in ETS-domain transcription factor function and regulation: lessons from the TCF (ternary complex factor) subfamily. The Colworth Medal Lecture.

The ETS-domain transcription factor family can be divided into a series of subfamilies. Elk-1 represents the founding member of the ternary complex factor (TCF) subfamily. By focusing on the TCF subfamily, we can demonstrate the complexities that exist in the function and regulation of ETS-domain transcription factors. This article focuses on Elk-1 in detail and summarizes the functions of other TCFs. The key themes covered include the domain structure of the TCFs, the mechanisms of complex formation with serum response factor, regulation of TCFs by mitogen-activated protein kinase cascades, and transcriptional regulatory properties of the TCFs. Finally, the emerging role of the TCFs in vivo is discussed. A picture is developing indicating that, while these proteins exhibit significant sequence and functional conservation, key differences in their structure and regulation are being identified which may relate to unique functions of these proteins in vivo.

Amino Acid Sequence↗

[Strained relations between federal health insurance and the public health service].

A close cooperation between all partners according to section 20 IV SGB V is basically welcome. However, in times of financial straits in public budgets, attempts have to be avoided to shift tasks and financial burdens to statutory health insurance (SHI). A series of examples shows that because of the different responsibilities-related to the insured persons on the one hand, and the general population on the other-tendencies to shift burdens to SHI are observed. However, such measures are neither adequate nor without problems (e.g. protection by vaccination). Public health service is requested to improve its epidemiological capacities and the qualification of its doctors. Furthermore, the service should be re-orient to a modern citizen-oriented service organization. Communities and provincial ("Land") governments have to provide the financial prerequisites.

Budgets↗

[Developing social medicine competence in medical education--goals in social medicine education for the practicing physician from the viewpoint of mandatory public insurance].

The social obligation of medicine is not limited to the application of technical-curative methods. It rather also encompasses prevention, rehabilitation as well as cooperation with other health professions. Furthermore, medicine is tied into a social, economical and legal framework which has a direct impact on medical practice. Training in social medicine within the medical curriculum has to address these relationships. Moreover, the interaction between the ecological, occupational and social environment and the causes of diseases and disabilities should be a central focus of the subject.

Clinical Competence↗

[Requirements for graduates of training courses from the viewpoint of various specialty fields].

By imparting competence in social medicine in the interdisciplinary course of studies "Public Health" graduates should be enabled to support social health insurance in finding adequate solutions regarding medical and economic aspects within the scope of planning and forming structures of health care. Thereby rationality in medical care can be increased so that rationing is avoided and reserves in efficiency and be mobilised.

Curriculum↗

[The concept of continuing education in medical service--competence of physicians in counseling in the field of (social) medicine, law and economics].

The paper describes the performance of continuing education programmes of the Medical Advisory Services in Germany and explains the methodical background. Elements of conceptional structure comprise basic and advanced seminars, professional und special training courses. Realizations of this training concept are described with special regard to demand, utilisation and acceptance with prospects of future.

Curriculum↗

[3 years of MDK (Health Insurance Medical Services)--current status and future trends].

The medical service and medical supply organizations operating in Germany within the framework of compulsory sickness insurance are based on the principles of common self-administration that is monitored via contracts. The partners to these contracts develop reciprocally adequate ideas on the medical and economic structures of the medical supply system and expand their supply and negotiation strategies by discussing the structures of paid benefits and medical supply. This means there is an increasing need for a medical interpretation of the findings and of the data on the course of a disease and its treatment. The need for explaining from a medical point of view why certain contract strategies have been adopted and must be followed, is also on the increase, as is the demand for quality assurance methods that can claim to be adequate for this medical supply system. Medical Advisory Service has become more distinctive wherever compulsory sickness insurance has been making every effort to shoulder its health policy responsibilities and to make quality assurance a declared aim.

Contract Services↗