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Biomedical subjects

H Rische

Publications and source records attributed to H Rische.

At least 37 records · Page 2Linked to original sources
PubMed1978

Enterotoxigenicity among salmonellae--a prospective analysis for a surveillance programme.

Gastroenteritis and food poisoning caused by several Salmonella serotypes are frequently observed in many countries. In particular, S. typhimurium has been found ranking first that put forward the question whether S. typhimurium can be characterized by distinct biological properties. In this paper attempts to characterized 378 Salmonella strains according to their enterotoxigenicity by means of the vascular permeability factor (PF) have been summarized. PF-positive strains are common among all Enteritis-Salmonellae, in particular among S. typhimurium. This serotype is also found with quantitative strongest PF activity. PF-positive strains are found to be active producers of exo-enterotoxins, which have been characterized as LT-enterotoxins by other assays, too. Since the capacity of Enteritis-Salmonellae to produce enterotoxins is in accordance with their clinical and epidemiological importance, the determination of the PF-factor as a rapid screening assay for enterotoxigenicity is proposed in this paper in order to survey epidemiological and clinical significant Salmonellae.

Animals↗
PubMed1977

[Chemotherapeutic strategy and chemotherapeutic regimes].

The problems arisen from plasmid mediated drug-resistance can only be solved by a chemotherapeutic drug policy with due regard to the different ecological processes. The antibiotic policy has the following purpose: 1. Estimation and prognosis of the use of chemotherapeutics in the therapy and prophylaxis of man and animals, the animal production, other paratherapeutic fields of application (feed-stuff industry, cosmetics etc.); 2. methods for the limitation of the spreading of infectious drug resistance; 3. production and import of chemotherapeutic drugs (inclusively antibiotics); 4. development of new drugs especially for their different application in medicine, veterinarian medicine and other fields. The drug policy is based upon the surveillance of infectious drug resistance and drug monitoring (effectiveness, economy, and side effects of the drugs).

Anti-Bacterial Agents↗
PubMed1977

Surveillance of R-plasmids.

The surveillance of R-plasmids consists of: (1.) Ecological and epidemiological investigations. (1.1.) Prevalence of R-plasmids in pathogenic and apathogenic bacteria occurring in the biotic environment (man, animal); in the abiotic environment (sewage, food, feed); under high selection pressure (hospital, animal production, plant production). (2.) Biological investigations. (2.1.) Genetic properties of R-plasmids: (2.2.) Plasmid induced variations of the properties of the host bacteria (virulence, phage pattern, antigenic pattern, serological properties). The problems resulting from plasmid-mediated drug resistance call for a strict chemotherapeutic drug policy with the regard to ecological processes.

Drug Resistance, Microbial↗
PubMed1976

[The incidence of frequently occurring Sh. sonnei phage types in the GDR].

On the basis of literature data (from 1955 to 1970) and own studies (from 1962 to 1974) the authors present information on phage types of Sh. sonnei the most frequently encountered in the GDR. It was possible to trace the detection and the incidence of individual phage types at the territory of the republic (by time). In centralized typing there were obtained rather constant and standard results. Further improvement of phage typing and also its complex use together with other methods of typing is necessary in epidemiological practice.

Bacteriophage Typing↗