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Biomedical subjects

H Rodríguez

Publications and source records attributed to H Rodríguez.

18 recordsLinked to original sources

[Inflammatory-type malignant fibrohistiocytoma of the mesocolon associated with colonic parasitosis due to Trichocephalus].

A case of inflammatory malignant fibrous histiocytoma of the mesocolon is reported. The lesion presented as a right lower quadrant abdominal mass, located at the mesocolon, with obstructive symptoms and accompanied by a severe infestation by Trichuris trichiura. It had a benign histologic appearance and was considered initially as an inflammatory and necrotic process with severe tissue eosinophilia secondary to the severe parasitosis. The tumor relapsed 13 months later at the anastomotic site and the patient died. Diagnostic, prognostic and therapeutic aspects of this rare tumor are discussed.

Aged

[Occult cancer in patients with symptomatic benign prostatic hyperplasia].

The results of a prospective study undertaken in 29 patients with symptomatic benign prostatic hyperplasia (BPH) are presented. Transrectal ultrasound, ultrasound-guided biopsy and prostate specific antigen (PSA) were utilized in the search for hidden cancer of the prostate. However, no cancer was detected in any patient. Very high values of PSA were found, particularly in patients with an indwelling catheter. Transrectal ultrasound yielded no false negatives and no complications were observed.

Adenocarcinoma

[Prevalence of risk factors for chronic diseases. A study in the general population of the metropolitan area, 1986-1987].

Risk factors for chronic diseases were studied in a random sample of 475 males and 728 females from the Metropolitan area of Santiago. A questionnaire was used to estimate the consumption of alcohol and tobacco and the level of physical activity. Weight and height were measured and socio-economic situation was classified according to Graffar. Prevalence rates for males and females were: hypertension 8.6 and 9.1%; obesity 13.2 and 22.7%; present sokers 50.7 and 43.4%; sedentarism 75.6 and 86.9%; alcohol consumption 56.2 and 19.8%. Thus, women show higher rates than males for hypertension, obesity and sedentarism. They smoked as much as males and consumed less alcohol. Among women a higher prevalence of obesity, alcohol consumption and sedentarism was observed in lower socio-economic classes. Among males, only sedentarism was more prevalent in lower socio-economic classes. The number of risk factors present was 1 in 28.6% of the population; 2 in 40.1%; 3 in 22.1%; 4 in 3.7% and 5 in 0.1%. Absence of risk factors was observed in only 5.4% of the population. The present data may help to design preventive strategies for diseases related to these risk factors.

Adolescent

Adult respiratory distress secondary to strongyloidiasis.

A patient with a renal transplant who was receiving immunosuppressive therapy developed the adult respiratory distress syndrome (ARDS). Numerous filariform larvae of Strongyloides stercoralis were seen in the bronchial lavage. The patient died despite intensive treatment, and the postmortem examination revealed abundant larvae of the parasite in the lungs. There were no other factors that could explain the ARDS.

Adult

[Primary sclerosing cholangitis. A report of 4 cases].

We informed four cases of primary sclerosing cholangitis associated with chronic ulcerative colitis, diagnosed in the Gastroenterology Department, Hospital de Especialidades del CM Siglo XXI Mexico City, during 1987 to 1988. The mean age was 30.2 years and the evolution of colitis was 6.6 years. Two patients were females and two males, all presented active colitis and three presented hepatic symptoms. The laboratory abnormalities were hypertransaminasemia, increased alkaline phosphatase and hyperbilirubinemia. In three patients endoscopic retrograde cholangiopancreatography was done, in all cases diagnosis was established by histology. The frequency of primary sclerosing cholangitis associated with chronic ulcerative colitis was 13.3%.

Adult

Occurrence of human papillomavirus type 16 DNA sequences and c-myc oncogene alterations in uterine-cervix carcinoma.

Using genetic engineering and molecular biology techniques, we have examined sixteen human carcinomas in the uterine-cervix tumors (the most frequent tumor in México, representing 34% of malignant tumors in women), for the presence of Human Papillomavirus type 16 (HPV-16) DNA sequences and possible alterations of the cellular myc (c-myc) proto-oncogene. In this study we have analyzed cervical carcinomas from patient with clinical stage II. We detected in 31% of these samples, the presence of HPV-16 sequences (2-100 copies). In addition, an elevated amplification (up to 80-fold in one tumor) and/or rearrangement of the c-myc oncogene was detected in most tumors (more than 90% of the samples). These results suggest that either c-myc oncogene and/or HPV-16 could play an important role in the development of uterine-cervix carcinoma.

Carcinoma