[Acid-base equilibrium in patients with chronic pulmonary disease].
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Biomedical subjects
Publications and source records attributed to H Romaldini.
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The case of idiopathic pulmonary hemosiderosis in a 20 year old male is presented. Iron deficiency anemia, recurrent hemoptysis and micronodular infiltrate in lower lung areas were the most important signs observed. The transbronchial biopsy showed alveolar and interstitial hemorrhage and hemosiderin in the pulmonary macrophages. Treatment was started with prednisone, but the addition of immunosuppressive drugs (cyclophosphamide) was needed, followed by a clinical remission.
The authors reviewed the actions of nifedipine, a blocker of calcium channels, on the systemic and pulmonary circulation. The mechanism of action of the drug on the systemic and pulmonary circulation and on the gas exchange is discussed. The main effects of nifedipine on the coronary circulation and indications for therapeutic use of the drug are discussed on the topics of coronary insufficiency, systemic and pulmonary blood hypertension, acute respiratory failure, and Raynaud's phenomenon.
This paper is a review of clinical and experimental studies on pulmonary hypertension in acute respiratory distress syndrome (ARDS) and its consequences on the outcome of such syndrome. The most probable causes: hypoxic pulmonary vasoconstriction, vasoconstriction provoked by vasoactive substances, extra and intraluminal occlusions are discussed. The authors also discuss the action of vasoactive drugs on the pulmonary circulation and on the pulmonary gas exchange.
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