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H Rousset

Publications and source records attributed to H Rousset.

At least 73 records · Page 4Linked to original sources
PubMed1993

[Enterovirus infections and systemic clinical manifestations with prolonged inflammatory syndrome: association with a persistence of specific IGM antibodies].

We report 9 cases of enteroviral infection associated with systemic inflammatory disease (including 4 cases of vasculitis, 1 case of periarteritis nodosa, 1 case of Sharp's syndrome). We then reviewed 36 cases of enteroviral infection with persistent IgM antibodies diagnosed in the virology laboratory in a 6-year period: among them 11 cases were found to present with subacute or chronic inflammatory disease. We conclude that enteroviruses might be important triggers of systemic inflammatory disease.

Enterovirus Infections↗
PubMed1993

[Systemic mastocytosis: incidence and risks of vasomotor seizures].

We report on 9 cases of systemic mastocytosis which underline the frequency and the potential severity of this disease. All patients had intercritical signs (usually urticaria). Seven patients had also typical crises with flush and vascular collapses are observed together, doctors should measure histamine blood level and perform correct biopsy.

Histamine Release↗
PubMed1993

[Unexplained chronic diarrhea, apropos of 4 new cases under Cyclo 3 fort and review of the literature].

We report 4 cases of chronic diarrhoea in patients treated with Cylclo 3 fort. This side-effect was not mentioned in the French list of therapeutic drugs until 1992. The diarrhoea was without faeces and without glairy mucus or blood. Symptomatic treatments were totally ineffective. The diarrhoea itself was well tolerated, but 3 patients lost weight, with hypokalaemia in 2 of them, and 1 had regressive acute renal failure. The time elapsed between the first dose of Cyclo 3 fort and the diarrhoea ranged from 1 to 3 months, and it took 5 months to make the aetiological diagnosis. Two patients were hospitalized. Withdrawal of the drug always resulted in cure. One patient taking enemas developed a regressive subocclusion of the bowel. The physiopathological mechanism of this diarrhoea is unknown. These cases are similar to the 5 other cases reported in the literature.

Acute Kidney Injury↗
PubMed1993

[Chronic fatigue syndrome: a critical review].

The term "chronic fatigue syndrome" (CFS) applies to a condition of unknown aetiology characterized clinically by an association of subjective symptoms, the most constant being an invalidating tiredness. The diagnostic criteria in current use do not permit to isolate an homogeneous subgroup among patients consulting for chronic asthenia. In the present state of research no infectious or immunological cause has been demonstrated conclusively, although a persistent enterovirus or herpesvirus type 6 infection or a state of chronic immune activation seem to play a role in some cases. Patients who fulfill the criteria of CFS present with psychiatric overmorbidity, essentially depressive, and in 50% of the cases with the mental disorders preceding CFS. The various theoretical models linking CFS to psychopathology are discussed, and finally the syndrome is regarded as a social construction reproducing or renovating the neurasthenia of the late 19th century. There is no specific treatment of CFS, but antidepressants, cognitive-behavioural therapy and perhaps certain immuno-modulators can be useful. The future lines of research should endeavour to isolate a subgroup of patients with prolonged asthenia after a recognized episode of infection and to identify the immunological, psychological and behavioral characteristics of this particular group as well as their reciprocal interactions.

Adult↗
PubMed1993

[A rare cause of loss of consciousness: mastocytosis. Apropos of 3 cases].

The authors report three cases of syncope due to systemic mastocytosis. This is a rare cause of syncope but should be recalled in certain circumstances. In the light of these cases, the authors review the literature with respect to this unusual presentation. Syncope may occur at any age. Loss of consciousness may be more or less complete, brief or prolonged, isolated or recurrent and usually accompanied by prodromal symptoms. The least controversial physiopathogenic mechanism of these syncopes is intense vasoplegia induced by the release of vasoactive mediators, especially histamine. When there is a clinical suspicion of mastocytosis, even in the absence of skin changes, the diagnosis is confirmed by biopsy which shows abnormally high numbers of mastocytes irrespective of the organ biopsied. The treatment of acute forms with collapse is based on intravenous infusion of macromolecular fluids and injections of epinephrine. Prevention is by drugs which inhibit the synthesis of histamine, the degranulation of mastocytes and the production of prostaglandin D2.

Aged↗
PubMed1993

[Painless infarction in antiphospholipid syndrome].

The authors report a rare case of myocardial infarction secondary to coronary thromboses caused by the antiphospholipid syndrome. The relations between the cardiac pathology, especially the coronary disease, and antiphospholipid antibodies are recalled. The importance and methods of monitoring the anticoagulant therapy are emphasised.

Anticoagulants↗
PubMed1992

[Contribution of chemiluminescence for determination of low value TSH in patients with dysthyroidism during negative TRH test].

TSH values performed by immunoradiometric method were compared with chemiluminescent method in 28 hyperthyroid patients with negative TRH-test. This last method gives a better sensitivity (0.020 mUI/L vs. 0.050 mUI/L) and reproducibility (5% V.C. vs. 40%). The measure of undetectable TSH by immunoradiometric assay becomes possible with chemiluminescence. Due to this increase of sensitivity, the TRH-test needs to be reconsidered and allows to discriminate various degrees of TSH suppression.

Adult↗
PubMed1992

[Eosinophilic ascites. 2 new case reports].

Two new cases of eosinophilic ascites and a brief review of 40 cases found in the literature are presented. In three quarters of the cases eosinophilic ascites affects women aged 40 years on average. Because the patients present with a history of allergy (55%), blood hypereosinophilia (69%), associated pleural effusion (11%), gastrointestinal disorders and, above all, eosinophilic infiltrations in the walls of the digestive tract or the serous membranes (63%), this pathology may be regarded as a clinical form or eosinophilic gastroenteritis. The outcome is favourable in 90% of the cases; relapses occur in 26%. Is eosinophilic gastroenteritis and independent pathological entity, or should it be considered a minor clinical form of Chusid's idiopathic hypereosinophilic syndrome? The lack of decisive arguments precludes a firm conclusion.

Age Factors↗
PubMed1992

[Facial hemiatrophy, homolateral cervical linear scleroderma and thyroid disease].

A case of facial hemiatrophy and homolateral cervical band of scleroderma, complicated by hypothyroidism is reported. This case raises two problems: one is the problem of distinction between Romberg's disease and facial hemiatrophy due to a genuine localized scleroderma; the other concerns the relationship between localized scleroderma and dysthyroidism. The generalized scleroderma-dysthyroidism association has now been recognized, but the coexistence of thyroid disease and localized scleroderma has not yet been reported. Several pathogenetic hypotheses on this association are discussed.

Facial Dermatoses↗
PubMed1990

[Acute lupus erythematosus disseminatus in adults: clinical aspects & course].

Acute systemic lupus erythematosus (SLE) is characterized by a variety of manifestations and by the almost constant presence of anti-nuclear antibodies. In order to distinguish it from other systemic diseases, eleven diagnostic criteria have been laid down, four of which at least must be present. In 50 p. 100 of the cases the disease is revealed by a non-destructive inflammatory polyarthritis which is highly suggestive when associated with a "butterfly" facial erythema. The main prognostic criteria are renal lesions and their histological type. Nervous system involvement seems to be less frequent and less severe nowadays, but it may leave sequelae. Pleuropericarditis and vascular thrombosis are commonly part of the clinical set up. Antinuclear antibodies are detected by immunofluorescence in more than 95 p. 100 of the patients, but they are not specific to SLE. Their absence in the initial phase of the disease may throw doubts on the diagnosis. Antibodies to DNA and Sm are more specific but inconstant. SLE is a chronic disease with intermittent flare-ups: 30 p. 100 of the patients may hope for a prolonged complete remission. At present, the survival rate at 10 and 20 years is higher than 80 p. 100 and 70 p. 100 respectively at the cost of a very close supervision but also of iatrogenic complications in increasing numbers.

Acute Disease↗