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Biomedical subjects

H Rozemond

Publications and source records attributed to H Rozemond.

15 recordsLinked to original sources
PubMed1990

[Animals in biotechnology: chip or resource].

Scientifically, a gene is a part of a chromosome regulating various biochemical processes. Ethically, it is an entity which may be used to influence life for better or for worse. This implies that genetic engineering with animals is only admissible when sound reasons are given. In this regard, there is a resemblance to experimental studies in animals. Two rules of conduct are suggested: (1) Biotechnological research, including genetic engineering, involving (farm) animals for the study and treatment of (genetic) disorders causing unacceptable stress or disease in man and animals, should be stimulated when adequate alternatives are not available. When doing so, adopting measures to minimise negative effects, particularly so in the animals themselves, should be a prerequisite. (2) Biotechnological applications in farm animals for the sole purpose of increasing production or other immediate material objectives should not be pursued, unless it is established that the welfare of the animals is not impaired and their integrity is properly ensured. When negative consequences can be expected for man or society, a solution of these problems should be devised beforehand.

Animal Husbandry↗
PubMed1989

[To the welfare of man and animals].

This inaugural address consists of three parts, starting with an elaboration of the fact that there is great differentiation among animals and humans. The second section goes into their interests. In the third section some practical relationships between humans and animals are discussed and some common denominators are sought. The title of the address is a well-known motto in the Dutch veterinary world: 'Hominum animaliumque saluti', which stands for: 'To the Welfare of Man and Animal'.

Animal Testing Alternatives↗
PubMed1986

Dutch legislation.

Explore the source record for details and available documents.

Animal Experimentation↗
PubMed1986

Laboratory animal protection: the European Convention and the Dutch Act.

The Council of Europe has adopted a Convention for the protection of vertebrate animals used for experimental and other scientific purposes. The Convention was opened for signature by governments of the affiliated countries on March 18, 1986. The government of the Netherlands signed on August 4, 1986. In this article, some aspects of the Convention are compared with current practice in the Netherlands under the Dutch Experimental Animals Act (1977). Special attention is paid to Animal Protection Officers and to problems in the assessment of severe and enduring pain in procedures with animals.

Animal Experimentation↗
PubMed1985

[Pain as a matter of conscience].

Veterinarians have a professional responsibility towards animals, owners and society. This responsibility is determined by understanding as well as by a sense of justice and fairness. Its relationship with all sorts of objections of a zootechnic, economic, social and ethical nature may be rather strained. This not only holds good for practising but also for dealing with animals intended for slaughter or experimentation as well as for acting in an official setting. When we look about us, views both on responsibility and the importance of objections are seen to be gradually changing. Pain and experience of pain as theme of this congress is symptomatic of this re-orientation. The first part of this paper is concerned with the manner in which these altered views are gradually gaining attention in society. The discussion is based on an elementary outline of the development of veterinary medicine, a differentiation being made between a mythical, a technical and a discerning approach. The second part is a discussion of the way in which veterinarians should cope with this criticism in their professional conduct. This is appropriate for two reasons. To begin with, veterinarians are becoming increasingly aware of the fact that they bear responsibility for the welfare of animals. Secondly, a point of view is expected of veterinarians in concrete situations.

Attitude of Health Personnel↗
PubMed1984

Recommendations for the housing of macaque monkeys.

A multidisciplinary working group was formed to make recommendations for housing of macaques under laboratory conditions in the Netherlands. The group concluded that long-term individual caging leads to persistent abnormal behaviour. Therefore, individual housing is regarded as acceptable only for special reasons which counter-balance the adverse effects of isolation. Guidelines are given for developing more satisfactory social housing systems. Cages used in individual as well as social housing should meet certain spatial and other requirements to ensure a certain amount of diversion, freedom of movement and safety. Since the recommendations represent the opinion of experts in certain aspects of animal husbandry, the report can be used as a legal reference under the Animal Experiments Act.

Aggression↗
PubMed1983

[The publishing of ethically questionable research. A commentary].

The question whether the editors of scientific journals should apply ethical criteria in addition to scientific and stylistic standards in assessing copy submitted, is discussed. This applies particularly to studies which cannot be justified by arguments that appeal to a large majority. Criticism of the ethical content of a paper may refer to the purpose of the study, the selection and treatment of the experimental subjects and the mode of presentation of the study. The publishing policy of the editors may have an effect on the ethical appreciation of problems arising in the course of their activities. The instruments available to the editors in this case are (1) refusing the paper or (2) accepting the paper with a view to provoking a discussion of the questionable point. The last-named possibility offers the additional advantage that those who are not directly involved will also be able to express an opinion.

Animals↗
PubMed1979

Detection of the K99 antigen of Escherichia coli in calf faeces by enzyme-linked immunosorbent assay (ELISA).

An enzyme-linked immunosorbent assay (ELISA) is presented for the detection of the K99 antigen of Escherichia coli in calf faeces. False-positive reactions were not observed with K99-negative strains and with several viral antigens. Only bovine coronavirus caused slight positive reactions which could be eliminated by a blocking test. As compared with the conventional procedure for the detection of the K99 antigen, ELISA seemed to be a least as sensitive and had the advantage that samples could be stored at --20 degrees C before testing. In addition many samples could be handled at the same time and the results became available quickly. By carrying out the assay as a blocking test, specific antibody against K99 in serum or colostrum could be detected and titrated.

Animals↗
PubMed1976

[E. coli enterotoxicosis in unweaned piglets. I. Some concepts (author's transl)].

In a brief review, attention is drawn to a number of findings on infections with enteropathogenic E. coli in suckling piglets: serological typinge K88 antigen, colonisation, enterotoxin production and enterosorption, absence of symptoms of inflammation in the bowel wall and significance of the various immunoglobulin classes. The term E. coli enterotoxicosis used to designate the disease is preferred to terms such as E. coli diarrhoea, E. coli enteritis and (enterotoxic) colibacillosis.

Animals↗
PubMed1976

[E. coli enterotoxicosis in unweaned piglets. IV. Evaluation of results obtained on using an adjuvant vaccine in the field (author's transl)].

The results obtained on using an adjuvant vaccine against enterotoxaemia caused by E. coli in suckling piglets are discussed on the basis of an inquiry conducted among a number of veterinary practitioners. The vaccine contains the OK groups O138:K81,K88, O141:K85ab and O149:K91,K88 and is administered parenterally to the dams during the latter half of gestation. The inquiry which covered 4,000 sows on fifty-five farms showed that, as regards diarrhoea during the first week of life, morbidity in the offspring of vaccinated sows decreased from 83 per cent to 6 per cent and that mortality dropped from 23 per cent to 0.3 per cent. Clinical results were slightly less satisfactory where diarrhoea during the second and third weeks of life was concerned. The importance of serological typing prior to vaccination is stressed. Abortion occurred in 0.5 per cent of the vaccinated sows within three days after vaccination. The question is raised whether there is a relationship between this vaccination and abortion.

Abortion, Veterinary↗