PubMed Health⌕ Search

Biomedical subjects

H S Khalil

Publications and source records attributed to H S Khalil.

9 recordsLinked to original sources
PubMed2006

Functional endoscopic sinus surgery for chronic rhinosinusitis.

BACKGROUND: Rhinosinusitis is a well-recognised clinical syndrome affecting patients of all ages and gender. FESS has now become a well-established strategy, comprising several techniques, for the treatment of chronic rhinosinusitis refractory to medical treatment. OBJECTIVES: The aim of this review was to assess the effectiveness of functional endoscopic sinus surgery as a treatment for patients with chronic rhinosinusitis. SEARCH STRATEGY: The Cochrane Ear, Nose and Throat Disorders Group Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (1966 to January 2006) and EMBASE (1974 to January 2006) were searched. Reference lists were handsearched and experts in the field contacted to identify further studies. SELECTION CRITERIA: Randomised controlled trials. Inclusion criteria were any of the following criteria singly or in combination: patients with chronic rhinosinusitis diagnosed by a health professional; patients with sinusitis symptoms for more than 12 weeks; endoscopic evidence of sinusitis or radiological evidence of sinusitis. Exclusion criteria were immune suppression; cystic fibrosis; Wegener's disease; previous sinus surgery or sinonasal malignancy. DATA COLLECTION AND ANALYSIS: All studies meeting the inclusion criteria underwent validity assessment and the data were extracted independently by the two authors. Comparisons were:FESS versus medical treatmentFESS versus conventional sinus surgeryFESS + medical treatment versus medical treatmentFESS + medical treatment versus conventional sinus surgery + medical treatment MAIN RESULTS: The three included studies were randomised controlled trials. The evidence available does not demonstrate that FESS, as practiced in the included trials, is superior to medical treatment with or without sinus irrigation in patients with chronic rhinosinusitis. A middle meatal antrostomy fashioned by FESS was also not shown to be superior to an inferior meatal antrostomy formed by traditional sinus surgery techniques, although the small sample size in the study does not exclude a type II error. In one study there was a relapse rate of 2.4% in the FESS and sinus irrigation group compared to 5.6% in the sinus irrigation only group. The relapse rates were not mentioned in the other studies. There were no major complications such as orbital injury or cerebrospinal fluid leak reported in any of the included trials. AUTHORS' CONCLUSIONS: FESS as currently practiced is a safe surgical procedure. The limited evidence available suggests that FESS as practiced in the included trials does not confer additional benefit to that obtained by medical treatment (+/- sinus irrigation) in chronic rhinosinusitis. More randomised controlled trials comparing FESS with medical and other treatments, with long-term follow up, are required.

Chronic Disease↗
PubMed2004

Schwannoma of the postcricoid region: report of a first case.

Schwannoma is one of the very rare benign tumours of the hypopharynx. It has to be distinguished from malignant tumours arising from this region. We report the management of a case of postcricoid schwannoma with a review of the literature.

Cricoid Cartilage↗
PubMed2003

Otoplasty for prominent ears in children. The technique adopted in the Portmann Institute.

The Otoplasty technique adopted in the Portmann Institute is a simple rapid technique that maintains the natural contours of the auricle with minimal risk of infection. The technique involves excision of a large ellipse of skin from the mastoid surface of the auricle and reflection of remaining skin to the edge of the helix. The subcutaneous and muscular tissues on the mastoid bone are excised and the mastoid surface of the auricular cartilage scored with monopolar diathermy. After haemostasis, the wound is closed using continuous long-term absorbable sutures. A dressing and bandage are applied and the child is monitored for 10 days. A head bandage is applied at night for one month with use of a sun-screen cream on the scar at daytime.

Academic Medical Centers↗
PubMed2003

The use of speech therapy in the treatment of globus pharyngeus patients. A randomised controlled trial.

INTRODUCTION: Globus sensation is a common condition accounting for about 4% of new referrals to an ENT clinic. A review of current theories on the cause of globus sensation concludes that no single aetiology is responsible. Wareing et al believed that globus sensation might in part be associated with excessive laryngeal and pharyngeal tension. The aim of this study was to substantiate in a controlled prospective manner the results of a non-controlled study by the same authors that certain speech therapy techniques improved globus symptoms. METHODS: 1. 36 patients with typical globus pharyngeus symptoms were randomised to treatment with speech therapy (Study group) and reassurance by nurse practitioner (Control group). The following data was collated for each patient: duration and type of globus symptoms (sense of a lump in the throat/throat irritation), severity of globus symptoms on a visual analogue scale, fibreoptic laryngoscopy, full blood count, barium swallow. 2. At the end of 3 months, patients in both groups marked on the visual analogue scale the severity of their symptoms. RESULTS: There was a significant improvement in the globus symptom scores in the speech therapy group compared to pre-intervention scores (p < 0.001, Wilcoxon rank test). There was also a significant improvement in globus symptoms in the speech therapy group compared to controls (p < 0.001, Mann-Whitney U test). CONCLUSION: Initial results suggest that patients with globus pharyngeus symptoms benefit from speech therapy.

Adult↗
PubMed2003

A simple assessment of quality of life in head and neck cancer patients; what can it tell us?

OBJECTIVE: A number of well validated quality of life (QoL) instruments are available. Head and neck cancer patients often find these exhaustive questionnaires too long or bothersome. The purpose of our study was to evaluate a patient self-reported very simple assessment of quality of life and to compare it with the well-validated European Organisation for Research and Treatment of Cancer (EORTC) QoL questionnaire. METHODS: A departmental simple questionnaire was designed consisting of 2 components: 1. A visual analogue scale; 2. A space for patients to enter up to 3 specific problems which prevent quality of life being better. These may be physical, emotional, social or practical problems. 112 patients attending the head and neck oncology clinic completed both questionnaires (half completed the simple questionnaire first and the other half the EORTC questionnaire first). RESULTS: There was a good correlation between the global health scores of the EORTC and the visual analogue scale of the simple questionnaire. There was poor correlation between specific domains in the EORTC questionnaire and the 3 comments mentioned by patients in the simple questionnaire. CONCLUSION: A simple patient assessment of quality of life can be used as a simple outcome tool in head and neck cancer data bases when specific details are not required.

Endpoint Determination↗
PubMed2000

Thyroglossal duct remnants.

Thyroglossal duct remnants presenting as a lump in the neck are usually called thyroglossal cysts. Meticulous dissection of the cyst and duct, along with the body of the hyoid bone (Sistrunk's operation) is necessary to avoid recurrence. The authors have reviewed the histology of 61 consecutive specimens diagnosed preoperatively as thyroglossal cysts and have found that a true cyst exists in only 46 per cent of cases.

Adolescent↗