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Biomedical subjects

H Satokawa

Publications and source records attributed to H Satokawa.

33 records · Page 2Linked to original sources

[Hemostatic changes after artificial valve replacement--especially tricuspid regurgitation].

To investigate hemostatic changes after artificial valve replacement, I studied platelets, fibrinogen (Fbg), antithrombin III (AT-III), fibrinogen degradation products (FDP), thrombotest (TT), prothrombin time (PT), bleeding time (BT) and activated partial thromboplastin time (APTT) in 75 patients complicated with combined cardiac valvular disease. Twenty-nine patients with tricuspid regurgitation (TR group) and 46 patients without that (control group) were compared. 1) TR group, that contained patients with severer cases, showed a significantly longer operative time and greater bleeding volume than control group (p less than 0.01). 2) Many patients in TR group showed high serum II, frequency of abnormal platelet functions during and after extracorporeal circulation total-bilirubin and GPT level after operation and higher ICG R-value before operation than in control group. 3) After operation, the platelet count was significantly lower in TR group (p less than 0.01) than in control group, and was lowest on the 3rd postoperative day in both groups. 4) In both groups Fbg increased significantly after operation, and was lower in TR group on the 7th and 10th postoperative days than in control group. FDP was significantly higher in TR group than in control group after the 3rd postoperative day. 5) BT and APTT were similar in the two groups. 6) PT and TT were lower in TR group before operation (p less than 0.01) than in control group, and decreased after operation and administration of anticoagulants in both groups. These results indicate that patients with combined cardiac valvular disease with tricuspid regurgitation have a hemorrhagic tendency due to disorders of extrinsic coagulant, which may be caused by liver hypofunction, and are easy to bleed.

Blood Coagulation↗

[Senile alteration of hemodynamics in surgery of abdominal aneurysm].

Hemodynamic measurements were performed before, during and after surgery of aneurysmal patients. Fifty non-ruptured infrarenal aneurysmal patients undergoing elective aortic reconstructions were studied. Patients who had no evidence of heart disease were divided into two groups by age. The older group consisted of 22 patients older than 70 years of age, and the younger group consisted of 28 patients younger than 70 years. The results may be summarized as follows: (1) Hemodynamics before surgery (volume loaded test): For 500 ml albumin infusion within 30 minutes, cardiac indices of the older group kept below 4.0 l/min/m2, whereas in the younger group there was an increase from 3.66 to 4.42 l/min/m2. (2) Hemodynamics during surgery: Peripheral resistance increased by cross-clamping of the aorta, and decreased after removal of the aorta, and decreased after removal of the cross clamp in both groups. Cardiac indices dropped during cross-clamping of the aorta. The older group dropped more noticeably compared with the younger group, for instance, at one minute after cross-clamping, the older group was 2.04 +/- 0.56, and the younger group was 2.44 +/- 0.56 l/min/m2. Mean pulmonary wedge pressure increased gradually during surgery in both groups. (3) Hemodynamics after surgery: The older group kept lower cardiac indices compared with the younger group, but not so noticeably. These results indicated that older patients have low cardiac function for preload and afterload change. We will be confronted by an increasing number of older patients in the near future. Hemodynamic managements of aortic reconstructions in the elderly might become important.

Age Factors↗

[A case of coronary artery bypass grafting with right gastroepiploic artery for right coronary artery obstruction associated with aortitis syndrome].

A case of a 66 year-old female with aortitis syndrome with right coronary arterial obstruction, was reported. The coronary arteriogram showed total occlusion of the right coronary artery (segment 2). On the aortogram, stenosis of the left common carotid artery, kinking and aneurysm of the descending thoracic aorta were revealed. Because she developed frequent attacks of effort angina and the descending thoracic aneurysm was small in diameter 38 mm, coronary bypass grafting to the right coronary artery was performed using the in situ right gastroepiploic artery. Postoperative course was not eventful and chest pain disappeared. In such cases, the right gastroepiploic artery is useful for coronary artery bypass grafting.

Aged↗

[Cardiac surgery of tetralogy of Fallot associated with DiGeorge syndrome: a case report].

A case of 7-year-old boy with tetralogy of Fallot associated with DiGeorge syndrome was reported. He had been diagnosed as cardio-facial syndrome with hypoparathyroidism because of hypocalcemia, convulsion, cardiac defect and the characteristic face. But immunologic study showed hypofunction of cellular immunity and cardiac catheterization and angiogram revealed the Tetralogy of Fallot. So we diagnosed as DiGeorge syndrome and performed operation. The thymus was not found and we close the ventricular defect with patch and reconstructed right ventricular outflow tract with transannular patch. We often measured serum ionized calcium level and corrected with calcium gluconate intravenously. Peritoneal dialysis was done due to oliguria and much inotropic support was necessary.

Child↗

[Pulmonary artery aneurysm-like associated with pulmonary stenosis].

A 55-year old man had complained shortness of breathing and an abnormal shadow at left hilus region had been pointed out on the chest X-ray film. Right heart catheterization and right ventriculography revealed pulmonary valve stenosis with pulmonary artery aneurysm-like. Utilizing cardiopulmonary bypass, aneurysmorrhaphy and valvotomy was performed. Postoperative course was good and he was discharged on the 29th postoperative day. It is considered that mild post-stenotic dilatation of pulmonary trunk due to pulmonary valvular stenosis might develop into the aneurysmal change because of some congenital structural deficiency in the pulmonary arterial wall.

Aneurysm↗

[A case of right aortic arch associated with subclavian steal syndrome].

A 20-year-old female of right aortic arch associated with subclavian steal syndrome is reported. She was admitted to our hospital for numbness of the left arm, headache and dysphagia. Division of the ligamentum arteriosum and left common carotid-left subclavian artery anastomosis were successfully performed.

Adult↗