Biomedical subjects

H Scemama

Publications and source records attributed to H Scemama.

3 recordsLinked to original sources

PubMed1995

[Value of controlled hyperstimulation in intrauterine inseminations].

85 patients, with various forms of infertility but who have at least one patent tube, were treated by superovulation with intra uterine insemination of sperm migrated on a discontinuous Percoll gradient. 231 cycles were carried out. 43 clinical pregnancies were achieved. 26 pregnancies were delivered. The mean cycle fecondity rate was 19% (43/231), 18% in the group of male infertility (13/72), 15% in the group of unexplained infertility (13/88), and 23% in the group of various subfertility factors (17/71). There was 20% of twins nor triplets neither quadruplets. There was no sever hyperstimulation. The role of superovulation, the interest of the technic in male infertility, the risk of hyperstimulation and multiple pregnancies are discussed in the text.

Adult↗

PubMed1982

[In vitro fertilization].

The results of 36 follicular punctures for in vitro fertilization (IVF) performed at the Maternity unit of Hôpital Tenon, Paris, between January and June 1981 are reported. To collect a pre-ovulatory ovocyte by follicular puncture through laparoscopy requires extremely accurate monitoring of ovulation to make sure that the ovocyte collected has completed its nuclear and cytoplasmic maturation in vivo. The criteria for puncture time are the beginning of LH plasma peak level in spontaneous cycles and injection of HCG in stimulated cycles. In this series the ovocyte collection rate was 60% on average. Failures were mostly due to the local status of the genital tract in the women selected for attempted IVF, since all of them had permanent tubal sterility consecutive to severe pelvic inflammatory lesions. The percentage of ovocytes found to be mature was higher in spontaneous than in stimulated cycles. Out of 13 pre-ovulatory ovocytes collected, 8 were fertilized in vitro. Four could be transferred into the uterus, resulting in two pregnancies which had to be interrupted at an early stage. IVF demands full availability of the surgical and laboratory teams concerned.

Adult↗

PubMed1981

[A comparative study of monitoring induction of ovulation using clomiphene and HMG-HCG. Hormonal and ultrasound profiles (author's transl)].

The authors have studied daily hormone monitoring (Estradiol 17B, FSH, LH, Progesterone) and ultrasound (the size of the follicles and the number of the follicles) in 17 inductions using Clomiphene and 16 using HMG and HCG in cases mainly of dysovulation, but also of anovulation, in women who had previously been treated by induction that had failed. They establish the difference in the results obtained as far as (Estradiol 17B concerned, as far as the number of follicle that were stimulated or the size of the pre-ovulatory follicle, according to whether Clomiphene or sequential HMG-HCG had been used as a method of induction. They analyse the liability of the criteria for screening by plasma levels and by ultrasound and the correlation between these two parameters.

Adult↗