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Biomedical subjects

H Scheunemann

Publications and source records attributed to H Scheunemann.

At least 19 recordsLinked to original sources

Congenital prearticular temporo-mandibular ankylosis in two siblings.

A report of congenital ankylosis of the temporo-mandibular joint has only very rarely been published. The existence of this entity has been met with great scepticism and therefore believed to be due to perinatal trauma and subsequent development of the ankylosis. However, publications are now available of observations at birth after an uneventful pregnancy and spontaneous delivery. Our cases are the first publication of congenital TMJ ankylosis in two siblings, although there are hints in the histories in two other papers that a sibling may have suffered from the same condition. We discuss the hypothesis that the potential to ankylose in the temporomandibular area is a congenital disorder as in our cases, and that even later in life trauma or infection are only supervening initiating factors.

Ankylosis

[Intubation with the new ultra thin flexible fiberoptic scope in small children with congenital ankylosis of the temporomandibular joints].

Management of anaesthesia and intubation using a flexible endoscope of the ultra-thin generation (external diameter on the distal end 2.7 mm) of brother and sister with congenital ankylosis of the temporomandibular joint is described. Sedation was provided with ketamine while maintaining spontaneous breathing. Alternative methods to overcome difficult intubation in infants and small children with consideration of their specific anatomical conditions are discussed. Insertion of a fiberoptic endoscope through the endotracheal tube in the age group reported here was not possible hitherto. The new ultra-thin generation of flexible fiberscopes now makes it possible to perform direct fiberoptic intubation of infants and small children.

Ankylosis

Diagnostic and therapeutic problems of myxomas (myxofibromas) of the jaws.

During the period from 1969 to 1977 11 cases of myxoma or myxofibroma in the jaw region have been treated at the Maxillofacial Surgery Clinic of the University of Mainz. Various kinds of diagnostic problems are discussed. We observed, inter alia, rapid tumour growth and a imitative dynamics in the radiographs, giving rise to a suspicion of malignancy in some cases. The locally infiltrative type of growth of myxomas must be taken into account during therapy, since insufficiently radical management is liable to be followed by a recurrence.

Adult

Bleomycin-sensitivity test: application for human squamous cell carcinoma.

Bleomycin (BLM)-inactivating enzyme activity, which is probably a parameter for the efficacy of this antibiotic in cancer therapy, was determined in biopsies from human carcinomas in the head and neck region. Twenty-three cases were studied. It was found that highly differentiated as well as moderately differentiated squamous cell carcinomas had low extractable activities of this enzyme, comparably to those found in normal skin tissue. Slightly differentiated as well as undifferentiated carcinomas (only one case) had increased enzyme activity. Parallel experiments estimating the total extractable thiol content in the biopsies gave no obvious correlation. The results are discussed in the light of the reported BLM efficacy in the treatment of differently differentiated squamous cell carcinomas.

Bleomycin

Nerve injury in fractures of the condylar neck.

Although fractures of the condylar neck belong to the most frequent injuries of the jaws, and various nerves are found in close proximity to the temporomandibular joints, only little mention is made in the literature of neurological complications arising from accidents. We have therefore carried out a prospective study on nerve injuries in 237 fractures of the articular process in the period 1971-1975. We found two cases of post-traumatic Frey's syndrome, whereby the syndrome developed from a post-traumatic auriculotemporal neuralgia. We also found loss of function of auriculotemporal buccal and facial nerves, and loss of taste sensation of the tongue in another case, caused by damage to the chorda tympani. This paper discusses the formal and causal origin of the individual damages, and suggests possibilities for their management.

Chorda Tympani Nerve