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H Scheurlen

Publications and source records attributed to H Scheurlen.

34 records · Page 2Linked to original sources

On the use of hazard functions in breast cancer studies.

Hazard functions are nowadays used extensively by mathematicians as a tool in the analysis of survival data. They have been implicitly employed in medicine for many years to investigate 'curability'. The hazard function will be shown to be a natural concept which can help the clinician to express in a precise way his ideas concerning the disease process and the biology of treatment effect. The relationship between hazard and survivor function is discussed. Some historical comments about the interpretation of statistics in survival time studies are also made.

Breast Neoplasms↗

[A controlled clinical study of early mobilisation of patients with myocardial infarction (author's transl)].

This is the report about 265 patients with recent transmural myocardial infarction. In the first week of hospital treatment 63 died. From the remaining 201 patients 101 fulfilled the conditions for early mobilisation of the WHO. In a controlled study these patients were divided in 2 groups: group 1 started the programme of early mobilisation the 7th day and group 2 was the control group which was mobilized after 3 weeks of bed rest. The 2 groups were comparable in the clinical course and had 2% of letality. The remaining 100 patients with conditions against early mobilisation were conservatively treated with 3 weeks of bed rest. The letality in this group was very high with 23%.

Age Factors↗

Hepatitis C-virus (HCV) antibodies in patients after kidney transplantation.

The hepatitis C-virus (HCV) is the main etiologic agent of posttransfusion hepatitis (PTH). Most patients depending on hemodialysis need transfusion of blood before kidney transplantation. Of 272 patients after kidney transplantation, 27 (10%) were found to be anti-HCV-ELISA-positive (HCV-Antibody-ELISA, Ortho Diagnostics). The antibodies could be neutralized by HCV C-100-3 antigen. Eight of 22 patients (36%) who had more than one kidney transplantation were classified anti-HCV positive [30% (8/27) of all anti-HCV positive patients]. The number of transfused blood units ranged from 0 to 99 BU. Receiving more than one kidney graft or the transfusion of more than 5 units of blood increased the risk for HCV infection 3.5 or 4.1 times, respectively, compared with one transplantation or less than 5 units of blood. No significant interactions were seen between these two variables. Of the anti-HCV positive patients, 48% were anti-HBc negative as well as HBs-antigen negative, 52% were anti-HBc positive.

Adult↗