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Biomedical subjects

H Schickedanz

Publications and source records attributed to H Schickedanz.

At least 55 records · Page 3Linked to original sources

[Sexual development of boys, treated surgically for dystopia of testicles (author's transl)].

A clinical follow-up examination was made in a group of 208 children and adolescents who had undergone surgical treatment for congenital cryptorchid testis (unilateral or bilateral) between 2 and 10 years before. The puberal growth and maturing process of the primary and secondary sex characteristics of this morbidity group was compared to that of normal juveniles. The examination was made according to clinical criteria: length and circumference of the penis, volume of testes, general development of the genitals, pubic hair. Compared to normal juveniles, the genital development of the children and adolescents of the follow-up examinations series was retarded.

Adolescent↗

[Evaluation of congenital-cryptorchid testicles after surgical treatment (author's transl)].

The volume of 271 congenital-cryptorchid testicles which were subject to surgical treatment was compared with that of 128 descended testicles of patients of the same age. Undescended testicles, also after successful surgical treatment, remain smaller on volume than descended ones. By means of the hitting method of the point counting technique the proportion of all seminiferous tubules in the total volume of one gonad can be calculated. The seminiferous tubules of congenital-cryptorchid testicles, also after intrascrotal replacement, maintain an essentially smaller proportion concerning the total volume as in descended testicles. Among the numerous methods of surgical treatment preference must be given to those which are especially favourable to the parenchyma.

Adolescent↗

[Studies on the growth of the width in seminiferous tubules of eutopic and congenitally dystopic testes in children and adolescents].

The average diameter of the seminiferous tubules is to be regarded as a criterion for the estimation of the morphological value of testicles. By means of 89 autoptically got preparations of regularly descended testicles the breadth-growth of the tubules depending on age in children was judged. Of 55 untreated congenital dystopic testicles morphometric determinations of the diameters of the seminiferous tubules were performed. At the same time 79 unilaterally and 78 bilaterally operatively dislocated, congenital dystopic testicles and 78 contralateral eutopic gonades were evaluated. The average diameter of the tubule of untreated dystopic testicles is significantly (p less than 0.001) smaller than the diameter of the orthotopic gonades corresponding to age. The average diameter of the tubule of operatively dislocated congenital dystopic testicles is, however, larger than the diameter of the untreated gonades corresponding to age. The earlier the treatment of congenital dystopic testicles is performed the larger are the chances of a development of the tubules corresponding to age.

Adolescent↗

[Length-growth of seminiferous tubules of untreated and as surgically displaced, congenitallydystopic testes in children and adolescents].

The total length of the seminiferous tubules of congenital dystopic testicles was calculated from bioptical preparations. 55 untreated testicles, 79 unilaterally and 78 bilaterally operatively displaced testicles as well as 78 contralaterally eutopic testicles were evaluated. During the whole prepuberal phase of life in the congenital dystopic testicles a nearly continuous growth of the length of the seminiferous tubules takes place. The total length of the intrascrotally displaced testicles is larger than the length of untreated testicles corresponding to age. After the operative correction of the position of congenital dystopic testicles an acceleration of the growth of the length of the tubule begins.

Biopsy↗

[Use of the 25-point ocular grid plate in quantitative-morphological studies of eutopic and dystopic testes of children].

From plains histologic preparations of children's testicles the volume of seminiferous tubules and extratubular tissue were calculated by use of the points counting method. In ectopic testicles, the extratubular part is significantly larger than in normally descended testes. The range of the values measured by this method diminishes the higher the total count of test points is. The 25-points-test-net of VEB Carl Zeiss Jena in particular met all requirements for quantitative examinations of the morphology of testicles.

Cell Count↗

[Effect of the fixation of biopsy specimens from rat testicles on the results of morphometric studies].

The kind of the fixation method of bioptic preparations of the testicles has a decisive influence on the morphometrically determinable average diameter of the seminiferous tubules. Under the same conditions experiments 207 preparations of the parenchyma of the testicles of rats were fixed in Bouin's and Carnoy's solution as well as in 10% formalin solution. The measuring values of the diameter of the tubules of the preparations fixed in Bouin's solution were largest. Therefore the authors recommend to perform the fixation of the bioptic preparations of the testicles in Bouin's solution. Thus standardized experimental conditions and possibilities of the comparison of morphometric findings may be got.

Age Factors↗

[Determination of the total length of seminiferous tubules in normally descended testes in children].

The total length of all seminiferous tubules of a testicle can be determined with the help of histomorphometric investigation methods. Two different methods are described and discussed. For this purpose bioptically got specimens of parenchyma of the size of a rice-grain are sufficient. In children the total length of the tubules constantly increases. During the prepuberal phase of life an acceleration of the growth of the length of the seminiferous tubules begins. The results of 89 autoptically got and morphometrically examined testicles of children are reported.

Adolescent↗

[Morphometric Investigations of Regularly Descended Testicles of Children (author's transl)].

On 89 regularly descended, autoptically obtained testicles, the following morphometric investigations were performed: Calculations of the volums, the mean diameter of the tubuli seminiferi, the total lenght of the tubuli, the mean content of spermatogonia per cross section of one tubulus seminiferus, and the total number of spermatogonia. The testicles evaluated have been obtained from children at the age of one day to fourteen years. The calculation of normal values of quantitatively assessed testicle structures are of fundamental importance for the estimation of the morphological significance of congenitally dystopic testicles.

Adolescent↗

[Pulmonary artery pressure in the pathophysiology of lung-resections therapy. Part I: standard values, surgical lung diseases, postoperative death rate (author's transl)].

The early death rate after lung-resections is caused mainly by right heart failure. The level of pulmonary blood pressure plays a decisive role in this respect. In patients with surgical lung diseases the blood pressure is significantly higher in several parts of lung circulation than in healthy persons. The early death rate after operation was found to be increased in patients with a higher level of preoperative pulmonary artery pressure.

Blood Pressure↗

[Pulmonary artery pressure in the pathophysiology of lung-resections therapy. Part II: bronchial carcinoma and pulmonary tuberculosis (author's transl)].

Patients with lung resections due to bronchial carcinoma have a much higher early death rate than patients with lung resections because of pulmonary tuberculosis. Functional failure of the cardiorespiratory system and right heart insufficiency are considered to be the main reasons for this difference. Intracardial pressure values were compared between 530 patients with bronchial carcinoma and 200 patients with pulmonary tuberculosis revealing significantly higher pressure values in the right heart and pulmonary artery for patients with bronchial carcinoma. Predisposing factors of the aged people are fundamental in this respect.

Blood Pressure↗