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Biomedical subjects

H Schwarzkopf

Publications and source records attributed to H Schwarzkopf.

At least 19 recordsLinked to original sources

[Early gastric cancer, results in a county hospital (author's transl)].

In a nine-year period, 46 patients with early gastric cancer were diagnosed and operated at a county hospital. Fiberscopy of the stomach raised the percentage of early gastric cancer from 1% in a five year pre-endoscopic period to 11.9% with endoscopy. On an average, subjects with early gastric cancer were 8 years younger than all cases with gastric carcinoma, those with the diffuse type according to Laurén significantly younger than those with the intestinal type, too. Postoperative mortality amounted to 6.5%; five more patients of 43 surviving the operation have died in the meanwhile. Besides synchronous and metachronous cancer in the resected stomach and other organs, late distant metastasis must be considered, too, in the follow-up of patients operated from early cancer of the stomach. These complications may endanger the five-years survival rate of 89% observed in the first series of our patients.

Adult↗

[The role of gastroscopy for preoperative reliability of diagnosis and operability in gastric cancer. Retrospective analysis at a county hospital (author's transl)].

The evaluation of 535 patients with gastric cancer observed in two 5-years periods with low (3%) and high (84%) preoperative endoscopic frequence demonstrated: 1. Change of the diagnostic procedure, mainly on the basis of out-patients examination, 2. a diminished role of preoperative X-ray examination for decisions about the further proceeding. 3. no more unnecessary probatory laparotomies without a lesion requiring surgery, 4. improved preoperative exclusion from surgery of patients supposed to be not operable, resulting in a reduction of explorative laparotomies and a relative increase of gastrectomies, and finally 5. a significant increase in early gastric cancer with a concomitant decrease of stage 2 and 3. The percentage of the largest group of gastric cancer in stage 4 remained constant, however.

Adult↗

[Diagnostic accuracy of fiber endoscopy in esophageal and gastric carcinoma. Attempt at error analysis].

A retrospective analysis was performed in 332 cases with cancer of the upper gastrointestinal tract. A limit of one month was set for delayed and missed bioptically verified endoscopic diagnosis. Malignant cycle in ulcerated lesions and the size of elevated processes were the probable causes of delayed diagnosis in 7 out of 37 cases with early cancer. In advanced gastric cancer missed diagnosis was probably caused by the indication for endoscopy made too late in an unknown number of cases or patient's refusal to undergo controls. However, failure of the endoscopist to recognize a malignant process must be considered too. The percentage of endoscopist's mistakes was below 2% in our series.

Aged↗

[Pancytopenia in diabetes mellitus treatment with tolbutamide?].

Pancytopenia developed in a 72-year-old woman after three years of tolbutamide treatment. When tolbutamide was discontinued and the usual treatment of pancytopenia undertaken, the anaemia persisted while the leukopenia and thrombocytopenia were reversed. Pancytopenia during tolbutamide treatment is extremely rare. But the blood picture and platelet count should be regularly checked in all patients receiving sulphonylurea drugs, ten days after starting treatment, every three months for the first year and then once yearly.

Aged↗