Biomedical subjects
H Seager
Publications and source records attributed to H Seager.
The effect of granule structure on the mechanical properties of tablets [proceedings].
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Relationship between granule structure, process of manufacture and tableting properties [proceedings].
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Improving the stability of a product containing inter-reactive ingredients: a comparison of different approaches [proceedings].
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Multilayered syrup granules--a method for improving product stability [proceedings].
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The measurement of moisture by infrared reflectance [proceedings].
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An instrumental method for the monitoring of mixing processes [proceedings].
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Dissolution and bioavailability of the anhydrate and trihydrate forms of ampicillin.
The solubilities and intrinsic dissolution rates of ampicillin anhydrate and trihydrate in distilled water and dilute hydrochloric acid at 37 degrees have been measured. The dissolution rates of these materials from loose filled hard gelatin capsules were determined and the in vivo bioavailabilities of the compounds compared. Small differences in the in vitro behaviour of the anhydrate and trihydrate forms were recorded but the in vivo availability of the two compounds was the same.