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Biomedical subjects

H Segal

Publications and source records attributed to H Segal.

At least 55 records · Page 3Linked to original sources

Heparin cofactor II levels are increased by the use of combined oral contraceptives.

Heparin cofactor II (HCII) was assayed by a microtitre amidolytic substrate technique. A linear response was obtained up to 1.5 U/ml and HCII levels were not affected by freezing and thawing the plasma. The assay was validated by comparing HCII and antithrombin III (AT III) levels in AT-III-deficient plasmas and samples from critically ill patients. Higher HCII levels were found in healthy normal women than in healthy normal men (means 1.16 and 0.97 U/ml, respectively, P less than 0.01). A significant increase in HCII levels from 0.86 to 1.10 U/ml (mean values) was seen in healthy normal women starting on combined oral contraceptive (COC) preparations (P less than 0.001). Increased HCII levels were maintained over a 6-month period, but fell towards normal 14 days after stopping COC, although they were still significantly higher than before starting COCs. The discrepancy in HCII level between normal men and women may be due to COC use. In clinical studies, different reference ranges should be used for men and women, and the need for careful questioning about the use of COCs is emphasized.

Adolescent↗

Sweating it out.

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Adult↗

Early infantile development as reflected in the psychoanalytical process: steps in integration.

The contention of this paper is that early infantile development is reflected in the infantile part of the transference. When it is well integrated it gives rise to an underlying non-verbal communication which gives a depth to other communications. When not integrated it gives rise to acting in as a primitive mode of communication. When this is understood the primitive experience can be integrated, symbolized and partly at least verbalized. The development of the infantile part can be followed in the fluctuating moves towards integration. Two examples are given. In one case I show how many analytical understanding leads to the integration of a split off primitive pre-verbal experience and the connexion of such integration with the development of speech. I also show how a failure of understanding on the analyst's part, repeating a developmental failure can affect this process adversely. In the second case I show integrative processes connected with weaning and the integration of the weaning process with genital sexuality.

Adult↗

Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain.

The effectiveness of nonprescription analgesics--acetaminophen and aspirin--in providing subjective relief of preoperative dental pain was evaluated in a varied population of adults. This study demonstrates for the first time the feasibility of evaluating preoperative analgesic efficacy in preoperative dental pain and provides evidence that acetaminophen (1 gm) and aspirin (1 gm) can alleviate dental pain better than a placebo.

Acetaminophen↗

A comparison of the relative efficacy of Serenace and chlorpromazine in the treatment of chronic schizophrenics.

A study designed to assess the relative efficacy of chlorpromazine and Serenace in the control of chronic schizophrenics is described. Twenty-five cases were selected for the study and were randomly allocated to treatment. The condition of the patients was assessed at fortnightly intervals over the eight-week duration of trial period. No significant differences in side-effects emerged in patients on chlorpromazine and Serenace in the dosages administered. The statistically significant trends all showed a superiority of Serenace above chlorpromazine which was in accord with the clinical picture.

Adult↗

On symbolism.

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Adjustment Disorders↗

Countertransference.

Countertransference can be used as an instrument in understanding the patient's projective identification. An analogy for the patient/therapist interaction is found in Bion's model of the infant's communicating by projection to the breast and the mother as containing and modifying such projections. The particular countertransference problems created by patients who have been objects of massive parental projections are examined. In such cases the patient's projections induce in the analyst diverse experience of past helplessness in relation to projections.

Countertransference↗