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Biomedical subjects

H Seidler

Publications and source records attributed to H Seidler.

14 recordsLinked to original sources
PubMed1992

Some anthropological aspects of the prehistoric Tyrolean ice man.

The corpse of a Late Neolithic individual found in a glacier in Oetztal is unusual because of the intact nature of all body parts that resulted from the characteristics of its mummification process and its protected geographical position with regard to glacier flow. Anthropological data indicate that the man was 25 to 40 years old, was between 156 and 160 centimeters in stature, had a cranial capacity of between 1500 and 1560 cubic centimeters, and likely died of exhaustion.

Animals↗
PubMed1988

[Approaches to the determination of social anthropologic status in Austria].

The variation of height and psychological test results based on the data of 22,872 Austrian conscripts (year of birth: 1964) was analysed, considering urban-rural and differences in occupation. The observed results are in accordance with the hitherto reported observations. It is seen that the social differences in body height are decreasing, whereas the social differences in intellectual capacities seem to increase.

Anthropometry↗
PubMed1986

[Variations in body height in 18-year-old males in Austria].

By means of the conscription data of the Austrian Army the variability of the height of 18 years old men from the age-classes 1962 and 1964, who come from three different Austrian provinces (Vienna, Niederösterreich and Burgenland) was analysed. In spite of the extensive data material it was nearly impossible to establish a causal interpretation beyond a pure description, because too many external additional informations are lacking. In all the three provinces a definite trend of acceleration was ascertained. Known social-anthropological facts could as well be confirmed, like the dependency of the height from school education in all the three provinces.

Adolescent↗
PubMed1979

[Effect of the phosphonic acid derivatives ethephon and trichlorphon on the incorporation in vivo of (14C)-acetate into cholesterol and other lipids in rats].

The effect of the phosphonic acid derivatives Ethephon and Trichlorphon on the incorporation of 14C-labelled acetate into lipids especially cholesterol was investigated. Adult Wistar rats were fed for 7 days diets containing 50 and 500 ppm, respectively, of the phosphonic acid derivatives. Both compounds caused a significant increase of the 14C-activity in lipids of serum, liver, heart, and brain. The effect of Ethephon was significantly more intense than that of Trichlorphon. The important finding was the Ethephon-induced increase of the [14C]-acetate incorporation into cholesterol which continued across all the tissues studied.

Acetates↗
PubMed1977

[Method for the control of (rat) liver functions by means of 14C-acetate for the toxicological analysis of foreign substances].

The authors present a test procedure which permits to obtain, by means of a single carbon-14-labelled compound as structural element in a series of essential substances, a survey of important fields of liver function. Special attention was paid to cholesterol. Methodical studies resulted in an optimization of the application under in vivo and in vitro conditions, and of the isolation of carbon-14-labelled cholesterol, ester cholesterol and glucose as well as of carbon-14-labelled phospholipids, triglycerides, bile acids, proteins and nucleic acids as groups. A comparison of the experimental techniques demonstrated the advantages of in vivo application. The method and its validity are illustrated by an example (DDT). Its use in studies on various active principles will be dealt with in future communications.

Acetates↗
PubMed1976

Metabolic and toxic behavior of phthalimide derivates. I. Fate of imidan in the fetus.

The organophosphate insecticide imidan includes a phthalimide group. Because of the structural relationship to the teratogenic compound thalidomide we have investigated its placental transfer and metabolic fate in rats. Its passage to embryonic tissues could be confirmed. After intraamniotic injection to the first amniotic cavity of the left uteri we could establish a distribution of imidan and 32P compounds throughout the uteri, the concentration depending upon the incubation time and the distances from the place of injection. The half-life of imidan, detected in the exterioized fetuses or in newborns, was 50--70 min. Imidoxon, i.e., the oxidized form of imidan, has a diminished half-life. This fact explicates the presence of imidoxon only in small concentrations after application of imidan.

Animals↗
PubMed1976

[In vitro behavior of 14C-lindane in blood].

Almost 55% of lindane (gamma-HCH) which had been applied in vitro are removed by simple hexane extraction of the blood; if blood fractions are extracted, a total rate of 95% results. The partition of gamma-HCH between the plasma and the erythrocytes is approximately I:I; when HCH erythrocytes are incubated in fresh plasma, almost 60% of erythrocyte HCH pass into the plasma. The erythrocytes absorb nearly 90% of the HCH contained in an aqueous medium. Haemolysis showed that HCH is most probably transferred through the membrane. The partition of HCH between the cytoplasm and the membrane fraction ranges from 3:7 to 7:3. TCA precipitates almost 90% of erythrocyte HCH together with the protein. The absorbing capacity of the erythrocytes could be followed up to nearly 0.4-10(-6)M/ml of blood. Cadmium increases, lead decreases the binding of HCH to the erythrocytes; mercury and ethanol exert but small effects.

Animals↗
PubMed1976

[Effects of DDT and lindane on thyroid function in the rat].

Using the previously described test method, the authors studied with the aid of iodine-131 labelled NaI the effects of daily doses of 30 and 75 mg DDT/kg of body weight, and of 12 and 36 mg of lindane/kg of body weight on the iodine and hormone metabolism in the rat. With DDT, the authors observed a marked increase of the thyroid mass and of the thyroid tri-iodothyronine and thyroxin levels and a simultaneous decrease of the thyroid iodine level. The values for serum iodine and protein-bound iodine were reduced. Serum thyroxin was slightly increased. Serum tri-iodothyronine was markedly increased, which was also true of the iodine fractions in the liver. Lindane was considerably less effective. Only the decrease of thyroid tri-iodothyronine and the simultaneous increase of thyroid thyroxin were striking. In the serum, both hormones remained unchanged. The values for the urine fractions of both the active principles were indicative of a hypofunction. The causes of the changes observed were discussed with regard to the findings of other authors. The present results permit the conclusion that the effects of the pesticides tested are obviously complex by nature.

Animals↗