The DPTI/STTI ratio as an estimate of the myocardial oxygen supply/demand ratio.
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Biomedical subjects
Publications and source records attributed to H Sigmund-Duchanova.
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A study has been undertaken to determine the accuracy of measuring oxygen saturation and oxygen content of blood with five different, commercially available systems. The indications for using them in medicine are discussed. In animal experiments simultaneous measurements were carried out with variations of oxygen saturation from 7% to 100%, of oxygen content from 0.1 vol% to 18 vol% and hemoglobin content from 5.5 g% to 18 g%. The Lex-O2-Con, the CO-Oximeter IL 182 and the Hemoximeter OSM2 are usable over the total range of variations, but the results of the AO-Oximeter are only correct in the range above 50% oxygen saturation. The information directly displayed by the In Vivo-Hämoreflektometer IVH3 are satisfactory, but its use obviously must be reserved for special situations which warrant the use of the catheter.
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The measurement accuracy of clinically applicable methods for blood flow measurement in coronary sinus -- continuous local thermodilution (LTD), differential pressure (DP), ultrasonic Doppler (US) and the electromagnetic flow measurement method (EMF) -- was examined in 15 anaesthetized closed chest dogs with left ventricle weights between 150 and 200 g. The LTD, DP, US and the EMF were examined in each experiment in the two following arrangements. 1. In coronary sinus -- left jugular vein by-pass: This arrangement allowed four reference methods for measurement of coronary sinus blood flow (CBF). 2. In "clinical" position, without by-pass, which allowed two reference methods for CBF measurements. The results on the measurement accuracy of the LTD, DP and US are, depending on the measurement arrangement, contradictory. In the by-pass arrangement 1 there was observed a good agreement of the LTD, DP and US CBF values with the reference values. In the "clinical" position, without by-pass 2 the measurement accuracy of LTD was not sufficient for exact measurement of CBF and derived parameters. The examined velocity tip flow probes (US, DP) gave no correlation with the reference methods. US and DP are even for semiquantitative estimation of CBF unsuitable. The EMF tip flow probe was for the CBF measurement unsuitable, because of disturbance by the electrical activity of myocardium.
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