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Biomedical subjects

H Sihm

Publications and source records attributed to H Sihm.

11 recordsLinked to original sources
PubMed1998

Fatty acid composition in serum among males 4-16 years after myocardial infarction.

In a case-control study we compared men who had suffered a myocardial infarction with age-matched controls free from clinically apparent ischemic heart disease. Our main interest were differences in serum lipid and apolipoprotein concentrations. We found no significant differences between these two populations. The fatty acid composition of the serum cholesterol esters was studied as an indirect measure of the dietary fat quality. There were rather small differences with regard to the fatty acid composition between the survivor cases and the controls suggesting that the quality of the dietary fat was not better among the cases after the myocardial infarction than among the average male in Kiruna. The cases had a significantly higher proportion of palmitoleic acid (16:1 n-7, p < 0.004) than the controls, also after controlling for other biomedical risk factors. A high content of palmitoleic acid may be a marker of increased risk for coronary heart disease.

Apolipoproteins↗
PubMed1997

Psycho-social risk factors for ischaemic heart disease among men in the subarctic area.

We analysed the psycho-social risk factors for acute myocardial infarction in Kiruna, a town about 150 km north of the Arctic Circle, with a high mortality in ischaemic heart disease. In a case-control study, 219 male patients aged 35 to 64 years admitted to Kiruna District Hospital, with a first acute myocardial infarction between 1973 and 1985, were compared to 438 age-matched male controls without coronary heart disease. After adjusting for main biomedical risk factors (diabetes, hypertension, number of smokers and family history) a combination of mental and physical stress at work (OR 3.5, 96% CI 1.6-7.8) and heavy physical work (OR 1.5, 95% CI 1.1-3.6) were associated with an increased risk of myocardial infarction, whereas good control over job tasks was associated with a reduced risk (OR 0.7, 95% CI 0.5-0.9). Migration into Kiruna, especially in the 15 years preceding the study compared to earlier migration, also appeared as an independent predictor of myocardial infarction. We conclude that subgroups of men in Kiruna are at particularly high risk of myocardial infarction because of adverse factors related to their work and their social life and thus enable to preventive measures.

Adult↗
PubMed1993

Risk factors for acute myocardial infarction among men in the subarctic area.

OBJECTIVE: To describe and quantify the main risk factors for acute myocardial infarction (AMI) among males in the subarctic region of Sweden. DESIGN: Case-control study comprising a questionnaire and a clinical examination. SETTING: Kiruna, a town about 100 miles north of the Arctic Circle with a very high mortality from ischaemic heart disease. SUBJECTS: 219 patients 35 to 64 years of age admitted to Kiruna District Hospital with a first myocardial infarction between 1973 and 1985, and 438 age-matched controls. RESULTS: The main risk factors for the whole group were hypertension (odds ratio [OR] 3.5), family history of AMI (OR 2.2), diabetes mellitus (OR 2.2), and smoking (OR 1.7). The distribution and strength of the risk factors differed between Kiruna-born and migrants into the community. CONCLUSION: Apart from the traditional risk factors, environmental and psycho-social factors and population dynamics must be taken into account when assessing the risk for a man in Kiruna of developing a myocardial infarction.

Adult↗