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Biomedical subjects

H Sośnik

Publications and source records attributed to H Sośnik.

At least 19 recordsLinked to original sources
PubMed1990

Histometry of male gonad in liver cirrhosis.

Left testicles of 125 male patients with cirrhosis and 124 control males were subjected to histometric analysis. The ages of the patients with cirrhosis ranged from 31 to 92 a (mean = 59 a) and in controls, it was from 17 to 87 a (mean = 53 a). In the testicles in cirrhosis, the mean partial value of the V% of the spermatogenic epithelium statistically decreased significantly by a factor of 1.21, that of Leydig cells by 1.32 and interstitial tissue by 1.23, while the mean value of V% of tubular membranes increased by a factor of 1.68 and that of blood vessels by 1.48. The mean partial area of the tubular cross-sections significantly decreased in the cirrhosis group by a factor of 1.3, and by the same factor, the mean number of tubular cross-sections increased per mm2 of the whole testicular sectional plane. The total volume of the tubular system decreased in cirrhosis by a factor of 1.4, and the total weight of Leydig cells by 1.8 in relation to the control group. In complete cirrhosis only, the mean partial area of tubular cross-sections decreased by a factor of 1.15, and the total weight of Leydig cells by 1.42 in relation to incomplete cirrhosis. The type of cirrhosis and the degree of its inflammatory activity were without any significant influence (with the exception of isolated elements) on the differences in the quantitative composition of testicular tissue. However, such effect was exerted by the degree of fatty infiltration of the cirrhotic liver.

Adult↗
PubMed1989

Correlation coefficient between the topological index of sudanophilic bodies (SLey) and various types of spermatogenic tubules in male gonad in human biomorphosis.

The purpose of the study was determination of the value of the correlation coefficient between the spermatogenic activity and the value of the topological index of the sudanophilic bodies (S.b.) in the ageing male gonad. The reported study was carried out on 61 left-sided testicles of individuals who died in traffic accidents or after myocardial infarction or stroke. Their ages ranges from 22 to 95 years (mean 55.2 years). A negative correlation was found between S Ley and tubules with highly progressed spermatogenesis, and a positive correlation between S Ley and tubules with arrested spermatogenesis. Of interest was the observation that the correlation became evident only in middle age. An unequivocal interpretation on these results are difficult. Further studies are suggested.

Adult↗
PubMed1988

Studies on the size of human male gonad in biomorphosis, alcohol intoxication, and cirrhosis--a review and own findings.

The size of the testicle (absolute weight, relative weight as the index X, length, and width was measured in 142 late patients aged 17 to 87 a (mean age = 54 a) serving as controls, in 193 deceased patients aged 20 to 81 a (mean age = 47 a) with a history of alcoholism, and in 136 defunct patients aged 30 to 92 a (mean age = 59 a) with cirrhosis. A significant difference in the mean size of the testicles was demonstrated between the cirrhosis group and both the control and alcoholism groups. No statistically significant differences was observed between the control group and the alcoholism group. The degree of acute alcoholic intoxication has no significant effect on the degree of testicular atrophy. Chronic alcoholism exerted a more significant effect on the degree of testicular atrophy than acute alcoholism. Coexistent cirrhosis increased this difference even more. The type of cirrhosis and the degree of its inflammatory activity had no significant influence on the testicular size. Such effect was demonstrated, however, if diffuse fatty infiltration of the cirrhotic liver was present. In the biomorphosis, the greatest mean testicular size was observed in the 4th and 5th decade of life. From the 6th decade on, the testicular size decreased statistically significantly. The curve of the values of the mean testicular size in alcoholism was more flat than in the control group and was situated below it. No statistically significant differences among the values of the testicular size in this curve were found. The testicular size curve in cirrhosis was below both these curves, and a statistically significant difference was found between the 7th and the 9th decades. The mean weight of the testicules in controls, alcoholics, and patients with cirrhosis was 17.58, 16.49, and 13.25 g, respectively, the mean volume was 16.37, 15.34, and 12.21 ml, respectively, the value of the index X was 2.47, 2.52, and 1.97, respectively, the testicular length was 5.05, 4.08, and 3.61 cm, respectively, the width was 2.93, 2.87, and 2.70 cm, respectively.

Adult↗