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Biomedical subjects

H Sonnenfeld

Publications and source records attributed to H Sonnenfeld.

17 recordsLinked to original sources
PubMed1985

[Congenital factor XII deficiency: a rare cause of increased activated cephalin time].

The fortuitous detection of an increased activated cephalin clotting time is often dependent on defects of the blood-clotting factors synthesized by the liver, haemophilia or von Willebrand's disease, circulating anticoagulants or specific deficiencies of various factors necessary for blood-clotting mechanisms. Much more rarely, it may be due to an isolated Hageman factor defect. This deficiency does not lead to an increased bleeding tendency and surgery has proved surprisingly uneventful. On the other hand, thromboembolic events may appear. Being and inherited disease with autosomal recessive transmission, the discovery of Hageman factor deficiency must lead to a complete family investigation.

Adult↗
PubMed1985

[Atracurium and cirrhosis: clinical study of the curariform action].

Hepatic function influences the action of muscle relaxants. Among these drugs, the elimination of atracurium does not depend on liver function. The clinical effects of atracurium were studied in ten patients with portal hypertension and some degree of liver dysfunction and in ten normal patients. The cirrhotic patients underwent resection of oesophageal varices while control patients underwent abdominal surgery. All patients received 0.6 mg X kg-1 atracurium as a first intravenous bolus injection and 0.2 mg X kg-1 incremental doses. The delay of action, the degree of neuromuscular block and the delay of reversal of the block were compared. No statistically significant differences were observed. It is suggested that non significant differences observed could be attributed to an increased volume of distribution of drugs in the cirrhotic patient. These results would suggest that atracurium may be the best relaxant in patients with severe liver failure.

Atracurium↗
PubMed1982

[Postoperative insulinotherapy. Methods and indications (author's transl)].

Postoperative insulinotherapy is widely used not only for diabetics, but also for patients suffering from glycoregulation anomalies induced by stress and parenteral nutrition rich in glucose. The authors point to recent progress in this field resulting from the development of new insulins and new procedures, such as continuous intravenous infusion with a constant flow. The correct management of insulinotherapy can be tabulated in accordance with different possible postoperative situations.

Diabetes Mellitus↗
PubMed1978

[Use of a new solution of synthetic amino acids in postoperative surgical intensive care. Evaluation of the value of nitrogen intake started in the immediate preoperative period].

A new synthetic amino acid solution, Totamine, was studied in pre- and postoperative surgical intensive care in order to determine the possible value of beginning high protein intake during the preoperative period. A comparison was made between two groups of 11 and 15 patients respectively, divided on a strictly random basis, receiving 1200 calories and 12.4 g of nitrogen per day in the forme of Totamine carbohydrate concentrate, starting two days before operation in one of them and on the day of surgery in the other. No statistically significant difference was seen. Calorific and nitrogen intake in both cases appeared to be satisfactory during the early preoperative period and both local and general tolerance of the amino acid solution was excellent. During the late postoperative period, there was a tendency to negativisation of nitrogen balance which justified an increase in calorific and nitrogen intake.

Adult↗
PubMedDate not supplied

Transfusion lung.

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Adolescent↗