[Hemodynamics of bullous emphysema - a new syndrome: cardiac tamponade emphysematous].
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Cardiac Tamponade↗
Biomedical subjects
H Sors
Publications and source records attributed to H Sors.
[Regional alveolar hypoventilation induced by alveolar hypocapnia (author's transl)].
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Arterial Occlusive Diseases↗
Synthesis of thromboxane B2 in incubates of dog platelet-rich plasma with arachidonic acid and its inhibition by different drugs.
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Animals↗
Improved sensitivity of iodinated histamine-prostaglandin radioimmunoassay by prostaglandin methyl esters.
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Cross Reactions↗
Diagnosis of pneumocystis pneumonia.
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Acute Disease↗
Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry.
A sensitive and specific radioimmunoassay using a 125I tracer of high specific radioactivity was developed for thromboxane B2 and was applied to the determination of the in vitro biosynthesis of this compound in some systems (i.e. human washed platelets, human platelet rich plasma (PRP) and rat spleen homogenates). The assays were also evaluated by mass spectrometry; levels measured by these two analytical methods were very similar. The results obtained for washed human platelets with a thin layer radiochromatographic method were in good agreement with the two preceeding methods.
Animals↗
Instability of 13, 14-dihydro-15-keto-prostaglandin E2.
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Animals↗
The use of iodinated tracers for a sensitive radioimmunoassay of 13,14-dihydro-15-ketoprostaglandin Falpha.
Radioimmunoassay of 13,14-dihydro-15-ketoprostaglandin Falpha is reported using various 125I-labelled derivatives. The apparent association constants of the antiserum for iodinated tracers are higher than with the homologous hapten. In spite of this, the high specific activities of iodinated tracers (2000 Ci/mmol) allow a 3-fold increase in the sensitivity of the assay when compared with the tritiated derivative. Human plasma levels of 13,14-dihydro-15-ketoprostaglandin Falpha reported (25+/-6 pg/ml) are lower than those previously found by radioimmunoassay, and no sexual difference was found.
Binding Sites↗
Recent aspects of prostaglandin biosynthesis: a review.
Some recent aspects of prostaglandin biosynthesis of physiological importance are reviewed. Particular attention has been placed on phospholipase functioning and inhibition, endoperoxides, thromboxane and prostacyclin (PGX) synthesis since these compounds are likely to be the potent biological derivatives of prostaglandin biosynthesis. Because of some recent studies, peroxidative reactions have been detailed; their intervention in prostaglandin biosynthesis is of importance and could explain some regulatory aspects of this process, as well as the action of several cofactors and prostaglandin synthetase inhibitors.
Amino Acids↗