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Biomedical subjects

H Stötzner

Publications and source records attributed to H Stötzner.

15 recordsLinked to original sources
PubMed1975

[Studies on the influence of body weight and form of therapy on the development of fatty liver in maturity-onset diabetes].

On the basis of our findings can be established that the frequent appearance of a fatty degeneration of the liver in diabetes mellitus is the resultant of a multifactorial disturbance, in which case above all the type of diabetes, the relative weight, disturbances of lipidmetabolism and the form of therapy are decisive for the size of the adipose degeneration.

Adult↗
PubMed1975

[Alcoholic hepatitis (author's transl)].

Among 64 patients with chronic alcoholic liver damage, alcoholic hepatitis was present in 30 cases. Varying degrees of inflammation with a different high amount of polymorphonuclear leukocytes as a consistent finding, hepatocellular necrosis, fatty change in the liver epithelium, hydropic swelling of some cells, liver alcoholic hyalin, bile duct proliferation and portal edema were found to be characteristic features of alcoholic hepatitis. Hepatocellular necrosis and fatty change in the liver epithelium always occurred in alcoholic hepatitis. There was a positive association between the severity of the remaining four histological features and that of the inflammatory basic finding. The characteristic inflammatory changes were often observed to be spotty in distribution.

Adult↗
PubMed1975

[Comparative light and electron microscopic study on liver cell inclusions in chronic alcoholic liver damage (author's transl)].

Liver cell inclusions in chronic alcoholic liver damage observed by means of the ligth microscope proved by correlated electron microscopy to be bile depositions, autophagic vacuoles, megamitochondria, alcoholic hyalin or accumulation of ribosomes. These liver cell inclusions are usually identifiable at the light microscopical level. The bile depositions undergo a lysosomal degradation. Thereby, they are converted into a pale brownish pigment and lose the property of reacting with histochemical bile tests. Owing to this brownish pigmentation bile depositions are distinguishable from the other mentioned liver cell inclusions under the light microscope. Autophagic vacuoles appear as eosinophilic inclusions and are PAS positive before as well as after the diastase treatment. On the contrary to these, the likewise eosinophilic megamitochondria are PAS negative, in the same way as alcoholic hyaline. With the procedure according to Goldner megamitochondria mostly strain red, whereas alcoholic hyalin lacks this property. Moreover, alcoholic hyalin is usually distinguishable from megamitochondria by its shape. Accumulations of ribosomes represent basophilic cytoplasm areas in light microscopy and are frequently located in he pericanalicular regions of liver epithelium.

Alcoholism↗