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Biomedical subjects

H Stich

Publications and source records attributed to H Stich.

At least 37 records · Page 2Linked to original sources

[Does bone metabolic activity determined scintigraphically correlate with calcium and phosphorus measurements by x-ray microanalysis?].

An animal experiment on bone healing of dental implants offered the opportunity of comparing scintigraphic images with histological findings, specially with electron microscope results and analysis of the calcium and phosphorus values in different stages. The clear correspondence between the scintigraphic results and the calcification level of the new bone parts must be seen with reservation because of possible methodical mistakes of the radio-micro-analysis from surfaces and of intraindividual differences.

Animals↗

Fixation of bone fragments with BIOCEM. First observations on humans.

BIOCEM is a recently developed material that consists of bisphenol-a-glycidyl methacrylate ("epoxide methacrylate") as the organic matrix and pentacalcium hydroxide triphosphate ("tricalcium phosphate") with or without bioceramic A2 as the filling particles. Previous animal experimentation has demonstrated that BIOCEM can establish and maintain direct contact with bone without compromising tissue vitality. Rather, it favors with time the ingrowth of, and coverage by, newly formed bone, thus creating interdigitations and strong fixation of the implant. This novel technique has now, for the first time, successfully been applied in humans, ie, for the fixation of frontal sinuses. Clinical, radiological, and histological findings are briefly reported, and it is also shown that the frontal sinus mucosa had recovered at the inside of the lesions filled with BIOCEM.

Adult↗

[Titanium-coated hollow screw and reconstruction plate system for the bridging of jaw defects. II. Possible reconstruction variants with the THRP system].

The advantages and special features of the THRP-system enabled us to develop new operative techniques. The combination of the advantages of external fixation devices and those of the internal osteosynthesis has proved to be decisive in order to obtain good results. The clinical results in 30 patients confirm the recently published findings from animal studies. Histological examination of human specimens comparing 2 types of screws developed by us are discussed.

Bone Plates↗

Use of the titanium-coated hollow screw and reconstruction plate system in bridging of lower jaw defects.

Clinical results obtained with hollow titanium screws and reconstruction plates in the bridging of mandibular bone defects of 17 patients are described. Following implantation the newly forming bone establishes direct contact with the sprayed titanium surface of the screw and the underside of the plate and permeates the screw. The stability of anchorage therefore increases with the duration of implantation. The reconstruction system also allows salvaging of small fragments such as the condyloid process. The adjustable, individually shaped, mandibular condylar prosthesis permits precise restoration of articular guidance on the reconstructed side while preventing incorrect loading of the opposite joint. The clinical results confirm the recently published findings from animal studies.

Adult↗

New concepts in the reconstruction of mandibular defects following tumor resection.

The results of experiments with a new reconstruction plate used to bridge defects in irradiated and nonirradiated mandibles of dogs are presented. The principles of fixation of the plate with hollow titanium powder-sprayed screws and a titanium mesh for stabilizing the autologous cancellous bone are discussed. The direct contact between the surface of the screw and the bone, as well as proliferation of bone into the hollow screw, are demonstrated by light and scanning electron microscope studies. Autologous cancellous bone fixed with the new mesh leads to bridging of the defect even in irradiated areas.

Animals↗

[Current possibilities of reconstruction of the lower jaw in bony defects following tumor resection. Animal experiments and clinical results].

The animal experimental methods as well as the clinical application in patients and histological results of a new reconstruction plate for use in bridging defects in the lower jaw are discussed. The principles of fixation of the plate with hollow titanium powder sprayed screws and a titanium mesh for stabilising the autologous cancellous bone are also given. Resection was carried out in irradiated and non-irradiated mandibles of dogs. The direct contact between the surface of the screw and the bone as well as proliferation of bone into the hollow screw are demonstrated by light and scanning electron microscope studies. New methods for the evaluation of the interface between implant and bone are described.

Animals↗

[Results of animal experiments following the use of a new material--biocement--for osteoplasty and fixation of alloimplants].

We report on results obtained with biocement (BC), a new material recently developed in our laboratory, in animal experiments dealing with osseous repair in the facial area. The organic matrix of BC corresponds to the Bowen formula. Anorganic filler substances comprise Ca5 (PO4)3OH, Bioceramic A2 (Battelle) and Bioglass Hench. We applied the new material to the following surgical interventions in monkeys or dogs: reconstruction of the anterior wall of the frontal sinus; covering of skull cap defect with or without a lesion of the dura mater; fixation of autologous bone transplants; bridging of defect in the mandible and the fixation of alloimplants under stress. The histological preparations of undecalcified bone were examined by light microscopy, in polarized light, with the help of scanning electron-microscope and the interface evaluation between implant and bone with energy dispersive X-ray analysis. Direct contact between BC and bone, and interdigitations between the two, as well as new bone formation were the rule. In addition, very few reactive changes were observed in cerebro-meningeal tissues neighboring BC. The latter did also not disturb the regeneration of ciliated epithelium in its vicinity.

Animals↗

The reactions of bone, connective tissue, and epithelium to endosteal implants with titanium-sprayed surfaces.

The results of a research project which has been under way for the last 7 years are reported. The project has been centred around a series of animal (monkey) experiments designed to test the suitability of cylindrical titanium implants with titanium-sprayed surfaces. The following results have been obtained: 1. The bone applies itself "ankylotically" (i.e. without an intervening layer of connective tissue) to the surface of the implant and, as revealed by observation over periods of up to 1 3/4 years, even remains attached to the implant surface when placed under load. 2. The fibres of the connective tissue between the bone and the epithelium insert into the titanium-sprayed surface and appear to be functionally orientated. 3. If the post of the implant is situated in a region of immobile, keratinized mucosa signs of adhesion of the epithelial cells to the titanium-sprayed surface become apparent. 4. The clinical success of the implant is clearly dependent on (a) the presence of tethered, immobile mucosa ("gingiva") around the post of the implant, and (b) perfect oral hygiene.

Animals↗