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Biomedical subjects

H T Paulk

Publications and source records attributed to H T Paulk.

3 recordsLinked to original sources

Herpes esophagitis in immunocompetent patients.

Although herpes simplex virus is a recognized cause of esophagitis in immunocompromised patients, it may also be the etiologic agent in otherwise healthy individuals. Odynophagia and dysphagia are the major symptoms. The esophagogram may reveal ulcers in the distal esophagus and there may be motor disturbances as well. Esophageal endoscopy may show vesicles, ulceration or plaques. In the immunocompetent patient, herpes esophagitis is a self-limited disease.

Adult

Thrombocytosis in Whipple's disease.

Three men with Whipple's disease had platelet counts of 729,000-1,142,000 per mm3, which fell to normal as their illness responded to antibiotic therapy. Reports on Whipple's disease and hospital charts from the largest published series reveal thrombocytosis in 11 of the 24 patients whose counts were recorded. The prevalence of anemia, marrow infiltration, and classic manifestations of Whipple's disease did not differ between patients with and without thrombocytosis. The thrombocytosis of Whipple's disease is similar to that of celiac sprue, Crohn's disease, and ulcerative colitis.

Adult