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Biomedical subjects

H T Xu

Publications and source records attributed to H T Xu.

4 recordsLinked to original sources

[Vitrectomy under temporary keratoprosthesis].

In vitreoretinal disorders complicated by corneal opacity, a temporary keratoprosthesis device is placed into a trephined opening in the cornea to provide a clear stable view which permits the performance of pars plana vitrectomy and immediately following the vitrectomy, the keratoprosthesis is replaced by a corneal graft. Using this technique, we have saved blind eyes with corneal and vitreoretinal disorders in one surgical procedure, being a new approach for rehabilitation of eye sight. Since 1990, the operation has been performed on 10 patients of whom 9 obtained satisfactory results. They were the patients who had been impossible to be saved by other methods and had been abandoned. The patient with the best result had been followed for 15 months and his visual acuity achieved and maintained 0.3. In six cases, the operation was combined with multiple procedures in the vitreous, such as gas fluid exchange, internal drainage of subretinal fluid, injection of silicone oil, etc. to facilitate the reattachment of the complicated retinal detachment.

Cornea↗

Immunomodulation of human cytomegalovirus infection on interferon system in patients with systemic lupus erythematosus.

On the basis of the research on the relationship between human cytomegalovirus (HCMV) infection and systemic lupus erythematosus (SLE) a study of the effects of HCMV infection on the immunological pathogenesis of SLE was undertaken. Presented in this paper is a brief account of the study. It was found that SLE patients with active HCMV infection had significant higher level of serum interferon-alpha (IFN-alpha) than those without active HCMV infection, but the IFN-alpha induction capacity of peripheral blood mononuclear cells (PBMC) from SLE patients with active HCMV infection was evidently poorer than that from patients without it. There was not any statistically significant difference between the two SLE groups in the IFN-gamma induction capacity of PBMC.

Adult↗

[Effect of Salvia miltiorrhiza on the left ventricular diastolic function in coronary artery stenosis].

In 24 open-chest mongrel dogs, coronary artery critical stenosis were produced by a micrometer constriction on left circumflex coronary artery. It was reduction about 87% in lumen area. CBF, -Vce, -dp/dt max were decreased, T was increased (P less than 0.01). 15 minutes after stenosis, the Salvia miltiorrhiza injection was injected into left atrium. CBF, -dp/dt max, -Vce were increased and T was decreased after the injection of Salvia miltiorrhiza. Moreover, the change of CBF was the earliest. The results proved that the Salvia miltiorrhiza could improve the left ventricular diastolic function in coronary artery stenosis.

Animals↗