H Takemi | PubMed Health

PubMed1984

Analytical isotachophoresis utilizing computer simulation. II. Assessment of optimum separation conditions for urinary trifluoroacetic acid metabolized from anaesthetic halothane.

Experimentally determined optimum separation conditions for a metabolite of anaesthetic halothane in urine, trifluoroacetic acid, were assessed by means of computer simulation of the isotachophoretic steady-state. The simulation confirmed that urinary acids and trifluoroacetic acid can be separated in the limited pH range of 3.5-3.7 buffered by beta-alanine, as far as the pH dependence of effective mobility is utilized. The separated fraction of the trifluoroacetic acid zone was identified by mass spectrometry. The simulated coefficient of the calibration curve agreed well with the observed value.

Computers↗

PubMed1980

81mKr gas generator for lung ventilation study.

A generator of 81mKr was designed and tested. The parent nuclide 81Rb was produced by the 70 MeV proton induced reactions on a Rb2SO4 target. 81mKr was bubbled out with oxygen gas from the 81Rb solution, and collected in a reservoir for lung ventilation studies. The generator was continuously operated at the high flow rate up to 10 1/min. The generator efficiency was 86%. The collection rates in the reservoir were examined under several flow rates. The pure 81mKr isomer was observed wih a NaI (T1) detector at the reservoir.

Humans↗