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Biomedical subjects

H Todorovicová

Publications and source records attributed to H Todorovicová.

At least 19 recordsLinked to original sources
PubMed1978

The transient loss of HLA antigens on lymphocytes in patients following administration of penicillin and tetracyclin.

Ten patients with inflammatory affections of urinary, respiratory and bile tract, as well as otitis patients were administered Penicillin. Six or seven days after the start of the treatment, four of them showed weakening or loss of minimally two earlier determined HLA antigens. The loss of HLA antigen was likewise demonstrated in a patient treated with Tetracycline. The HLA antigens were reliably demonstrated again six to seven days after the end of the treatment. The results suggest a possible false typing of HLA antigens in patients who had been administered Penicillin or Tetracycline. In accordance with Ben-David et al. [1] transient loss of two HLA antigens with concomitant development of lymphocyte polyreactivity was found in one of four patients treated with Chloramphenicol.

Anti-Bacterial Agents↗
PubMed1977

Decomposition of molecular types of triglycerides by lipoprotein lipase in man.

1. The lipoprotein triglycerides of human plasma can be separated by gas chromatography according to their carbon number into four main groups: C48, C50, C52 and C54. We studied the decomposition of molecular types of triglycerides by posttheparin lipoprotein lipase in vitro. 2. Decomposition of the molecular type C52 does not depend on its concentration. Decomposition of the molecular types C48, C50 and C54 is in a direct correlation to their concentration. 3. The above mechanism assures stability of the triglyceride profile of human plasma, which is species specific and is expressed by the figures: C48--9%, C50--20%, C52--43%, C54--20%, remainder 8%. 4. The plasma triglyceride profile can be altered by dietetic factors. After drinking cream, the triglyceride composition is: C48--12%, C50--22%, C52--37%, C54--14%, remainder 15%. Selective decomposition of molecular types of triglycerides ensures that the profile, after a given time, returns to the original state.

Dietary Fats↗