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H Toomes

Publications and source records attributed to H Toomes.

77 records · Page 5Linked to original sources

[Surgical position and possibilities in bronchial carcinoma].

In accordance with international statistics 25% of all patients with bronchogenic carcinoma can be treated by resection at the moment the diagnosis is established. The 5 year survival rate is in most series 25%. Important prognostic factors are: TNM-stage, histological classification, biological nature of the tumour and involvement of lymph nodes; discussed are further localisation of the primary tumour and immunological status. The summarizing statistics show that the carcinoma of squamous cell type has the best chance of a 5 year survival with a rate of more than 50%. In small-cell carcinoma extremely different 5 year survival rates between 0 and 20% are reported. In the surgical treatment it is obvious that the number of lobectomies are increasing in comparison to pneumonectomies. The postoperative mortality rate differs for "radical" pneumonectomy between 20% and 35%, for simple pneumonectomy between 7% and 10% and for lobectomy below 2%. Determinant for the postoperative course is the preoperative estimation of the risk factors. The 5 year survival rate after broncho- or angioplastic procedures varies in different series between 9,8% and 36%. In segmentectomies and wedge resections the 5 year survival rate was up to 56%. Primary palliative resections are indicated for pain reduction and improvement of the quality of life.

Adenocarcinoma↗

[The transmediastinal pleurotomy (author's transl)].

A new surgical method is presented, the transmediastinal pleurotomy. With this technique it is possible to explore the opposite lung from a standard thoracotomy and to perform diagnostic or therapeutic resections in suitable cases. So far we have performed 20 transmediastinal pleurotomies without any complications.

Humans↗

Resection of pulmonary metastases from renal cell carcinoma.

Between 1980 and 1995, 77 patients underwent complete resection of pulmonary metastases from a renal cell carcinoma after exclusion of a primary tumor recurrence and other metastatic localizations. 30-day mortality was 3%. The Median follow-up was 34 months (M). Cumulative 5-year survival (5-YS) was 39%. Prognostic criteria are the duration of the disease-free interval (DFI) and the number of metastases. Patients with a DFI > or = 48 M had a 5-YS of 46% compared to 26% for a DFI of < 48 M. Patients with a solitary metastasis had a 5-YS of 49% compared to 19% for multiple metastases. There was no significant difference in terms of sex, kind of access, kind of operation, and unilateral or bilateral affection. Since metastases from renal cell carcinomas are almost resistant to chemotherapy and radiotherapy and immunotherapy at present does not considerably improve long-term survival, surgical resection currently is the only effective therapeutic access in renal cell cancer metastasized to the lung.

Adult↗

Operative thoracoscopy for recurring pneumothorax.

Video-assisted thoracoscopic surgery has markedly changed the management of recurrent pneumothorax. Thoracotomy is no longer the routine approach for the surgical treatment of bullae, partial pleurectomy, or various methods of pleurodesis. Many surgical procedures on the lung and the pleura can be performed endoscopically as safely and easily as in open thoracic surgery. These new techniques have been assessed in 94 patients. An early analysis of the postoperative data shows that the minimally invasive procedure reduces postoperative discomfort and the length of hospital stay; the rate of recurrence is no higher than that for open pneumothorax surgery.

Equipment Design↗