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Biomedical subjects

H Verneyre

Publications and source records attributed to H Verneyre.

At least 19 recordsLinked to original sources

[Cerebral abscess disclosing congenital heart disease].

Cerebrovascular accidents and brain abscesses are the most worrisome complications of cyanogenic cardiac lesions in infants and young children, but remain rare in the adult. The authors report the case of a brain abscess which led to the subsequent discovery of a congenital cardiac malformation consisting of a ventricular septal defect and moderate pulmonary valve stenosis. Complete correction of the cardiac lesions was carried out three months after neurosurgical treatment (needle biopsy/drainage).

Brain Abscess

[Spontaneous angina caused by spasm of the left coronary artery].

A 42 year old woman presented with a one year history of retrosternal chest pain and back pain on effort and at rest sometimes accompanied by minor syncopal attacks. Transient atrioventricular block was documented during one such episode associated with hypotension. Coronary angiography showed spontaneous spasm of the left main coronary artery with clinical symptoms but no electrocardiographic changes. The spasm was relieved by injection of SIN-1. The similarity between the previous clinical symptoms and those observed at coronary angiography was in favour of the diagnosis of spasm of the left main coronary artery without atherosclerotic coronary disease. Treatment with calcium atherosclerotic coronary disease. Treatment with calcium blockers and platelet antiaggregants led to total regression of her symptoms with a follow-up of 5 months.

Adult

[Torsades de pointes and prolongation of the duration of QT interval after injection of droperidol].

Following a case of torsades de pointe (TDP) after the injection of droperidol (D), the authors studied the electrocardiographic variations caused by the drug. Fifty five unselected patients under the same conditions (general anesthesia) were given D (0.25 mg/kg IV). Significant prolongation of the QT interval was seen in 70% of cases by the end of the first minute. QT interval and the ratio of QTm (measured) over QTt increased from 387 +/- 34 ms to 423 +/- 37 ms (p less than 0.0001) and from 1.06 +/- 0.08 to 1.28 +/- 0.1 (p less than 0.001) respectively. These changes could favourise the onset of TDP. Although exceptional in terms of the extensive use of the neuroleptic in question, this possibility indicates the need for monitoring of the duration of QT before and during treatment with droperidol and for prescription of the drug to be avoided in circumstances known to be propitious to this arrhythmia (bradycardia, hypokalemia, anti-arrhythmic drugs).

Adult

[Spontaneous calcified coronary embolism and myocardial infarction. Apropos of a case].

The authors report a rare case of myocardial infarction due to calcific coronary embolisation in a patient with previously asymptomatic calcific aortic stenosis. The diagnosis was suggested by the finding of a lacunar image in the distal segment of the left anterior descending artery exactly corresponding to a punctiform mobile calcification visible before opacification of the coronary arteries. The clinical features of coronary embolism and in particular of calcific embolism are reviewed.

Aortic Valve Stenosis

[Echography and scintigraphy using technetium 99m pyrophosphate in the diagnosis of cardiac amyloidosis].

The diagnosis of amyloid cardiomyopathy was only based, until the last few years, on the results of invasive techniques. It seems presently that the combined contribution of cardiac sonography and scintigraphy using technetium 99m pyrophosphate, makes, most of the time, this diagnosis possible without need for additional examinations. This notion is illustrated by a typical case-report and data from the literature. Demonstration on the cardiac sonogram of a thickening of the walls-while the context and especially the electrocardiogram are not in favor of a left ventricular hypertrophy--associated with a very particular "hyperechoing" aspect and an abnormal fixation on the scintigram, may be considered specific of this disease.

Amyloidosis

[Traumatic coronary-cardiac fistulas. Apropos of a case].

The case of a 24-year old patient having suffered a bullet wound was reported. After a hemopericardium accompanied by minor signs of tamponade, a continuous murmur gradually appeared due to a fistula between the right coronary artery and the right atrium, which was strictly symptomless: surgical repair was performed eight years after the accident. This satisfactory spontaneous outcome, after surviving the life threatening danger of tamponade and myocardial infarction was also observed in the 21 cases of coronary-cardiac fistulae already published. The fistula, which almost always involves the right heart cavities, only gives rise to a continuous murmur which is often discovered at a later stage. The long term course of traumatic coronary-cardiac fistulae can only be assessed by comparison with congenital coronary-cardiac fistulae, which are much better known, and the consequences of which are on all accounts similar. Four complications are discussed: heart failure, coronary insufficiency, infectious endocarditis, and the rupture of the fistulized coronary artery due to aneurysmal dilatation. These risks are statistically small and more theoretical then real, and the justification of systematic repair of traumatic coronary-cardiac fistulae now rests essentially on the relatively low risk of the procedure.

Adolescent

[Clinical considerations apropos of 51 cases of cardiothyrotoxicosis].

A series of 51 cases of thyrotoxicosis gathered during a period of 6 years in a department with a cardiological orientation is analysed. This peculiar form of thyrotoxicosis is often unrecognized in view of its frequent occurence in aged subjects (which is misdiagnosed as "senile heart") and of the incidence in its causality of a toxic adenoma, the endocrine semiology of which is often reduced. In front of any case of heart failure of unknown cause, one should systematically think of a thyroid aetiology. A persistent sinus rhythm is not enough to discard it. A low cholesterol rate should induce to continue the investigation. The subnormal character of the classical laboratory parameters (including the thyroid hormone assay) does not always make it possible to exclude definitely the diagnosis. When the clinical picture is suggestive, only the radio-isotope examination with dynamic tests is liable to provide decisive data.

Adenoma

[Pheochromocytoma disclosed by isolated inflammatory syndrome].

Among the atypical forms of phaeochromocytoma the isolated inflammatory form is rare and difficult to diagnose clinically. The authors report such a case, where computerized tomography and magnetic resonance imaging contributed enormously to the diagnosis.

Adrenal Gland Neoplasms