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Biomedical subjects

H W Bause

Publications and source records attributed to H W Bause.

14 recordsLinked to original sources
PubMed1996

Toxic megacolon caused by cytomegalovirus colitis in a multiply injured patient.

Cytomegalovirus (CMV) colitis is a rare event that has been described mainly in immunocompromised patients with immunosuppressive medication or HIV infection. An association with severe trauma has not been described previously. We report a formerly healthy, multiply injured 75-year-old male who subsequently developed what appeared to be pseudomembranous colitis. By the time the diagnosis of toxic megacolon on the basis of CMV colitis was established, he had succumbed to multiple organ failure. Whenever pseudomembranous colitis is clinically suspected but not confirmed in a critically ill formerly healthy patient, CMV colitis should be excluded. Once the diagnosis is confirmed, generous resection of all affected colon is mandatory in view of the limited benefit of antiviral therapy in CMV-induced toxic megacolon.

Aged↗
PubMed1993

Postoperative pulmonary complications in patients with esophageal cancer.

There are recent reports on postoperative pulmonary complications in patients with esophageal cancer who were treated preoperatively with chemotherapy and irradiation. The Hamburg Esophageal Study Group is currently undertaking a prospective randomized study to evaluate the efficacy of preoperative treatment. Postoperative pulmonary complications and mortality in these patients with either a combined preoperative treatment (group 1, n = 11) or chemotherapy alone (group 2, n = 9) are evaluated in the present paper. Complete remission of the tumor was found more often in group 1 (54.6%) than in group 2 (22.2%). However, postoperatively the patients of group 1 developed adult respiratory distress syndrome (ARDS; 54.6%) more frequently than in group 2 (11.1%), and all patients with ARDS died. Thus, although the combined preoperative treatment is more effective in tumor remission, it is associated with a higher respiratory failure and postoperative mortality. Therefore, the preoperative regime has now been changed by the study group. Since after the clinical manifestation of ARDS no causative clinical therapy is available up to now, attention must be focused on the prevention of respiratory failure.

Aged↗
PubMed1990

[The lateral thoracic radiograph in the intensive care unit using digital luminescence radiography].

The digital luminescence radiography (DLR) technique is being used increasingly for clinical diagnosis, particularly in intensive care . Since the installation of a DLR unit, we have carried out more than 20,000 examinations of the chest on patients in intensive care. 12.1% of these were lateral radiographs. In this way, the diagnosis can be made of the extent of a pleural effusion, the presence of a ventral pneumothorax or of atelectasis. Using DLR, these examinations can be carried out at the bedside and have improved the radiological investigation of patients in intensive care.

Humans↗
PubMed1988

[The chest picture in the intensive care station as visualized by digital luminescence radiography].

To date there have been occasional reports on the technical aspects and accounts of the clinical use of digital radiography. There has, however, been a lack of reports on the clinical use of the technique in a large number of patients. We report our experience concerning more than 1250 chest x-rays on patients in intensive care; these have been carried out since December 1987, using a digital system. The method produces improvement in the radiological diagnosis of patients in intensive care; this is due to avoidance of incorrect exposures, the ability to obtain lateral films, consistent exposures and the ability to manipulate and store images electronically.

Humans↗
PubMed1983

The influence of an angiotensin II antagonist, saralasin, given before donor nephrectomy, on kidney function after transplantation. A controlled prospective study.

Kidneys from cadaver donors who had been treated during the last 10 min before bilateral nephrectomy with an infusion of 10 micrograms/kg-1/min-1 (Sar1, Val5, Ala8)-angiotensin II had a remarkable, significantly lower percentage of acute renal failure (25%) after renal transplantation than untreated kidneys (58.3%). Anuria was seen in the treated group only in 4.2%, although it occurred in the untreated control group in 16.6%. The role of the activated renin-angiotensin system in postischemic acute renal failure is discussed.

Acute Kidney Injury↗
PubMed1983

[Filter attachment].

The filter attachment enables rapid and continuous transfusion of stored erythrocytes and of stored whole blood. This attachment is used both with a microfilter and a largepore transfusion device. The filter attachment enables bloodless preparation of the transfusion. The blood volume previously remaining in the microfilter, can now be transfused completely.

Blood Transfusion↗
PubMed1981

[Death by obstructive asphyxia: the pathophysiology of respiration and hemodynamics (author's transl)].

The pathophysiology of respiration and hemodynamics during the agonal period of death by obstructive asphyxia was investigated. Experiments were carried out on ten dogs that were strangulated by ligature (seven cases) or asphyxiated by occlusion of the intubation tube (three cases). The following parameters were registered: Blood pressure in the arteria femoralis and arteria pulmonalis, electrocardiogram, endotracheal pressure, respiratory frequency, electroencephalogram. These were the most important findings: (a) An excessive and distinctly biphasic hypertonic reaction takes place after strangulation by ligature whereas occlusion of the intubation tube results in a slight increase of arterial blood pressure. (b) After occlusion of the tube more than after strangulation the endotracheal pressure becomes deeply negative during the inspiration trials. (c) After cessation of respiration a distinct pulmonary arterial hypertension develops in both forms of obstructive asphyxia. (d) The paralysis of the respiratory center takes place after about 4 min at the same time when the circulatory breakdown develops. The final cardiac failure occurs after about 9-10 min. The dysregulation of respiration and hemodynamics in the agony of obstructive asphyxia can be differentiated from other shock models. This results in special morphological alterations of the lung tissue which have been described elsewhere.

Airway Obstruction↗
PubMed1978

[Long-term measurement of arterial blood pressure via the superficial temporal artery (author's transl)].

The method used for prolonged continuous measurement of arterial blood pressure in surgical intensive care unit is describe. It was employed in 150 persons aged 1--65 year for periods of up to 30 days. It involved arteriotomy of the super-ficial temporal artery followed by the insertion of a catheter. The absence of side-effects in any of the 150 patients makes this technique very suitable for prolonged continuous blood pressure measurements.

Adolescent↗