PubMed Health⌕ Search

Biomedical subjects

H W Jordan

Publications and source records attributed to H W Jordan.

At least 19 recordsLinked to original sources
PubMed1990

Tardive dyskinesia successfully treated with alprazolam.

Tardive dyskinesia is a disorder secondary to prolonged treatment (from 18 months to 3 years) with antipsychotic agents, affecting approximately 15% to 20% of patients. Tardive dyskinesia is characterized by difficulty controlling involuntary movements of the small muscle groups, producing tic-like reactions, muscle rigidity, and difficulty maintaining muscle tone. It is a chronic and unrelenting disorder which may be permanent if not successfully treated. The mechanism of action is thought to be secondary to dopamine hypersensitivity resulting from prolonged deprivation of dopamine on the part of dopamine-sensitive receptors. Theoretically, these receptors have been deprived of the neurotransmitter by chronic treatment with antipsychotic drugs, which are recognized as dopamine-blocking agents. We present a case in which alprazolam was successfully used in treating tardive dyskinesia.

Adult↗
PubMed1989

Involutional paranoid disorder: a forgotten syndrome.

Involutional paranoid disorder is seen frequently in medical and psychiatric inpatient units, geriatric units, and other medical settings in which persons in the climacteric age group are treated. Little information is provided in the recent literature to guide the practitioner in diagnosing and treating this disorder. The authors review the clinical features of involutional paranoia and present three case reports to illustrate the characteristic symptoms. Diagnostic and treatment considerations are also reviewed.

Aged↗
PubMed1986

Post-traumatic stress disorder: a psychiatric defense.

Post-traumatic stress disorder (PTSD) is one of the anxiety disorders recently included in the Diagnostic and Statistical Manual of Mental Disorders, Third Edition (DSM-III).(1) The disorder refers to the psychological sequelae that may follow a significant stressor. The military has previously referred to PTSD as "war neurosis," "shell shock," and "combat neurosis."PTSD has recently gained attention as a means of legal defense. As a defense, it may exist separately from "innocence by reason of insanity." The authors review the literature, provide case vignettes exemplifying the clinical features, and present three additional cases that gained local and national notoriety because of their defense motions. The senior author served as an expert witness in these cases. Recommendations are given to readers who may in the future serve as expert witnesses or consultants in similar cases.

Adult↗
PubMed1983

Munchausen's syndrome or chronic factitious illness: a review and case presentation.

The psychosomatic disorder termed Munchausen's syndrome has gained official recognition in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, in which it is referred to as a "chronic factitious disorder with physical symptoms." Sporadic case reports have been published over the years. Few patients with this disorder allow themselves to be psychologically evaluated or seek treatment for the disorder itself. We report here an unusual case in which a young woman sought help for her hospital-peregrinating behavior.

Adult↗
PubMed1980

Communication between cancer patients and physicians.

A total of 185 practicing physicians in middle Tennessee responded to a questionnaire regarding their communication patterns with cancer patients. This represented 61% of a total of 320 area physicians to whom questionnaires were mailed. Nearly 98% of responding physicians always or usually inform patients that they have cancer. No difference in communication was noted as a function of specialty or age. A number of terms are used at different times during the course of a patient's illness.

Adult↗
PubMed1980

De Clerambault syndrome (erotomania): a review and case presentation.

A syndrome which was first described by G.G. De Clerambault in 1885 is reviewed and a case is presented. Popularly called erotomania, the syndrome is characterized by the delusional idea, usually in a young woman, that a man whom she considers to be of higher social and/or professional standing is in love with her. She develops an elaborate delusional process about this man, his love for her, his pursuit of her, and her inability to escape his "affectionate clutches." This syndrome may persist for a period of a few weeks to a few months in the recurrent form and be replaced by a similar delusion about another man. In the fixed form, which is the example of the case being presented here, it may persist for several years. The patient presented here has experienced this syndrome for eight years; there are reports in the literature of persons maintaining the syndrome for longer than 25 years.Patients with this syndrome may be diagnosed as having paranoid vera or other forms of paranoid disorder, or as paranoid schizophrenic. In light of the overwhelming nature of the delusional process affecting this patient's total life experience with marked delusions of persecution, grandeur, jealously, and self-depreciation as well as ideas of reference (illusions), and agitated and sometimes bizarre behavior, it seems quite appropriate that her diagnosis may be termed schizophrenic reaction, paranoid type.The literature is surveyed in depth and the case is presented in sequential detail.

Adult↗
PubMed1975

Fine structure of lymphocytes from an immune deficient child before and after administration of transfer factor.

Lymphocytes from a male infant delivered by Cesarean section and placed into a germ-free environment were examined by electron microscopy (EM). The child had a sex-linked severe combined immunodeficiency. The lymphocytes were atypical, having sparse cytoplasm with little rough endoplasmic reticulum (ER) but abundant smooth ER. The nuclear membrane was pulled away from the nuclear space, and no evidence of nuclear pores or aggregated ribosomes was found. Mitochondria were intact. Repeated injections of the subject during the 9-month period with KLH, typhoid vaccine, and diphtheria toxoid yielded no significant observable change in the fine structure of the lymphocytes. At 11 months, the subject was given transfer factor. Following repeated injections of this material, the original cell type was still present but a new type of lymphocyte was also observed by EM examination. The new cell type resembled a more normal lymphocyte. It had a higher density of cytoplasmic material, in comparison with cells prior to administration of transfer factor. It was smaller in size with some aggregated ribosomes, had detectable amounts of rough ER, and more intact nuclear membranes. This new type of lymphocyte may represent a small population of B lymphocytes perhaps stimulated by T cells made immunocompetent by transfer factor.

Cell Nucleus↗