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Biomedical subjects

H W LAWS

Publications and source records attributed to H W LAWS.

9 recordsLinked to original sources

PERIPHERAL VASODILATORS IN THE TREATMENT OF MACULAR DEGENERATIVE CHANGES IN THE EYE.

Four peripheral vasodilators - tolazoline HCl (Priscoline), nicotinic acid, nicotinyl alcohol (Roniacol), and nylidrin HCl (Arlidin)-were studied in 203 patients over a 13-year period as treatment for macular degenerative changes in the eye.Visual acuity was improved or maintained in 87%. Excellent results were obtained in the treatment of macular edema following cataract surgery and in older patients with diabetic retinopathy. In 126 out of 145 patients with senile macular degeneration, improvement or stabilization was obtained.For all the types of macular degeneration, nylidrin HCl was the most effective of the drugs studied and had the fewest side effects.A recent report based upon animal experiments advises against the use of peripheral vasodilators in degenerative arterial diseases of the eye; however, the assumption made therein that blood volume is a measure of blood flow cannot be accepted. Peripheral vasodilator therapy, which long-term clinical study has shown to be valuable in the treatment of macular degeneration, should not therefore be denied to these patients.

Aged↗

STRABISMUS IN GENERAL PRACTICE.

Considerable confusion exists concerning the time at which a cross-eyed child should be referred to an ophthalmologist. This referral should be made between six and nine months because visual and muscular coordinated reflexes necessary for normal vision and stereopsis develop at six months, and 80% of these reflexes are established by the age of two. Normal anatomical relations must be established shortly after six months to avoid the formation of fixed, irreversible, abnormal reflexes which lead to loss of vision in one eye and lack of stereopsis.The recommended classification of crossed eyes emphasizes the insidious divergent type that must be treated in infancy.Reasons for delay in referring cross-eyed children include incorrect advice from the family doctor and inappropriate advice from optometrists. Treatment is aimed at the development of normal vision in each eye, stereopsis, and a good cosmetic result.

Adolescent↗