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Biomedical subjects

H W Meyer-Rüsenberg

Publications and source records attributed to H W Meyer-Rüsenberg.

11 recordsLinked to original sources

Enhancement of spontaneous fibrinolytic activity in diabetic retinopathy.

The fibrinolytic system was studied in 96 patients with type I diabetes mellitus. Patients were grouped according to their degree of retinopathy; 38 patients with no evidence of retinopathy, 28 patients with background retinopathy and 30 patients with proliferative retinopathy. Thirty healthy individuals served as controls. The basal fibrinolytic activity as measured by clot lysis time and t-PA activity was increased in diabetic patients. This was associated with low levels of plasminogen activator inhibitor. Increased levels of D-dimer in diabetic patients further indicate enhanced in vivo fibrinolysis. The increase in fibrinolytic activity was highest in diabetics without retinopathy, and decreased with increasing retinopathy. Endothelial release of t-PA after venous occlusion was not different between controls and all diabetic groups. These findings suggest that in type I diabetics the fibrinolytic system is in an activated state. With worsening of retinopathy this increase in fibrinolytic activity diminishes.

Adolescent

[Bulbar dislocation].

A luxation of the ocular globe can occur spontaneously or due to an adequate trauma. In the older literature several case reports are quoted. The authors report an ocular luxation of a four-year-old girl after a bicycle accident. The reaction of the affected eye's pupil was negative as well as the consensuel reaction of the other eyes's pupil. Three hours after the trauma the bulb was replaced under general anesthesia. There was a macular edema with a central red spot. Nevertheless a control after four weeks proved visus of both eyes and stereopsis to be normal. It is concluded that--as known from the older literature--an ocular luxation does not necessarily mean avulsion of the optic nerve and amaurosis. Thus, a rapid reposition ought to be attempted.

Child, Preschool

[Ear cartilage as tarsus replacement (with long-term results)].

The authors report on 52 lid operations in combination with the transplantation of ear cartilage to serve as tarsus. The preoperative diagnoses were: ectropion (22); entropion (5); tumors (18); lid reconstruction following trauma (7). The long-term results were determined in 24 patients with 29 lids, with an average follow-up time of 26 months. The lid margin fit and the cartilage was palpable in nearly 90% of the long-term results; 83% of the patients were content with the cosmetic outcome.

Cartilage

[Interface echos between the retina and choroid].

In 61 patients echographically examined in A and AB mode at Münster University Eye Hospital a membrane-like echo was found between the retina and the choroid. The acoustic characteristics were studied. The usefulness for the differential diagnosis of retinal detachment was demonstrated with several situations of the retina. The thickness of the retina and choroid can be measured in routine examinations.

Choroid

[Long-term prognosis in primary glaucoma in childhood].

The authors report on long-term observations of patients who underwent surgery for congenital glaucoma between 1961 and 1976. It was possible to perform follow-up examinations in 46 out of 100 patients. In 66 out of 73 eyes (90%), intraocular pressure was regulated to below 22 mm Hg appl. after periods ranging from 5 to 22 years, in 16 eyes with additional local treatment with beta-blockers. Over 60% of the cases had central vision better than 0.4, and only 2 of the patients had to be educated in special schools. All of the others were at least capable of attending elementary school and 50 percent of them were even able to go on to higher schools.

Adolescent